Surface immunoglobulins of erythrocytes and platelets in dogs naturally infected by Rangelia vitalii

Rangelia vitalii is a protozoan of the Babesiidae family that parasitizes domestic and wild dogs in South American countries. The main laboratory findings in blood samples from animals infected by R. vitalii are anemia and thrombocytopenia. The aim of this study was to detect IgM and IgG immunoglobu...

Full description

Saved in:
Bibliographic Details
Published in:Microbial pathogenesis 2018-08, Vol.121, p.245-251
Main Authors: França, Raqueli Teresinha, Pillat, Micheli Mainardi, da Silva, Cássia Bagolin, Schafer, Andressa Salvadori, Dornelles, Guilherme Lopes, Costa, Márcio Machado, Chaves, Rafael Oliveira, de Andrade, Cínthia Melazzo, Erhardt, Magnólia Martins, Antoziazzi, Alfredo Quites, Ulrich, Henning, da Silva, Aleksandro Schafer, Lopes, Sonia Terezinha dos Anjos
Format: Article
Language:English
Subjects:
Animals
Blood Platelets - chemistry
Dog Diseases - blood
Dog Diseases - parasitology
Dogs
Erythrocytes
Erythrocytes - chemistry
Female
Immune-mediated thrombocytopenia
Immunoglobulin G - blood
Immunoglobulin M - blood
Immunoglobulins
Male
Piroplasmida - isolation & purification
Platelets
Rangeliosis
Receptors, Antigen, B-Cell - blood
Thrombocytopenia - blood
Thrombocytopenia - parasitology
Tick-Borne Diseases - blood
Tick-Borne Diseases - parasitology
Tick-Borne Diseases - veterinary
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Rangelia vitalii is a protozoan of the Babesiidae family that parasitizes domestic and wild dogs in South American countries. The main laboratory findings in blood samples from animals infected by R. vitalii are anemia and thrombocytopenia. The aim of this study was to detect IgM and IgG immunoglobulins on the surface of red blood cells and platelets, as well as to determine the percentage of reticulated platelets and reticulocytes in dogs naturally infected by R. vitalii. Blood samples from twenty dogs seen at the Veterinary Hospital of the Federal University of Santa Maria (UFSM) were divided into two groups: the diseased group consisted of blood samples from 10 animals with the diagnosis of rangeliosis, and the healthy group (control) consisted of samples from 10 healthy animals. All diseased dogs showed normocytic normochromic anemia but showed no differences (p > 0.05) in reticulocyte counts compared to healthy dogs. Moreover, IgM and IgG immunoglobulins were detected on the surface of the plasma membrane of red blood cells from both groups, but the amounts did not differ between groups (p > 0.05). Thrombocytopenia in infected animals was classified as severe. The percentage of reticulated platelets was higher (p 
ISSN:0882-4010
1096-1208
DOI:10.1016/j.micpath.2018.05.036