Nocardia infection over 5 years (2011-2015) in an Italian tertiary care hospital

This study was conducted reviewing clinical records of 14 patients affected by nocardiosis over 5 years in a tertiary care hospital. Nocardia abscessus was responsible for one third of infections, deviating significantly from the results reported by other epidemiological investigations and highlight...

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Bibliographic Details
Published in:The New microbiologica 2018-04, Vol.41 (2), p.136-140
Main Authors: Mazzaferri, Fulvia, Cordioli, Maddalena, Segato, Edoardo, Adami, Irene, Maccacaro, Laura, Sette, Piersandro, Cazzadori, Angelo, Concia, Ercole, Azzini, Anna Maria
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Antibiotics
Carbapenems
Drug Resistance, Bacterial
Epidemiology
Female
Humans
Infections
Italy - epidemiology
Male
Middle Aged
Nocardia
Nocardia - drug effects
Nocardia - isolation & purification
Nocardia Infections - drug therapy
Nocardia Infections - epidemiology
Nocardia Infections - microbiology
Nocardiosis
Retrospective Studies
Tertiary Care Centers
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Summary:This study was conducted reviewing clinical records of 14 patients affected by nocardiosis over 5 years in a tertiary care hospital. Nocardia abscessus was responsible for one third of infections, deviating significantly from the results reported by other epidemiological investigations and highlighting the key role of molecular identification tests. Indeed, a precise identification of species is crucial for the determination of antibiotic sensitivity patterns and, consequently, for the choice of antibiotic treatment. Noteworthy, 40% of isolates of N. abscessus (formerly N. asteroides complex) showed resistance to carbapenems, which are usually recommended for empirical therapy.
ISSN:1121-7138