Chloroquine –Induced Hair Depigmentation

A case of hair depigmentation induced by chloroquine diphosphate subacute overdosage in an 11-year-old patient with dermatomyositis is presented. Normal coloured hair growth occurred after normalisation of chloroquine dosage. A discussion on possible pathomechanisms of this phenomenon is made based...

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Bibliographic Details
Published in:Lupus 2009-03, Vol.18 (3), p.264-266
Main Authors: Di Giacomo, TB, Valente, NYS, Nico, MMS
Format: Article
Language:English
Subjects:
Anti-Inflammatory Agents, Non-Steroidal - adverse effects
Child
Chloroquine - adverse effects
Chloroquine - analogs & derivatives
Dermatomyositis - drug therapy
Drug Overdose
Hair Color
Humans
Hypopigmentation - chemically induced
Male
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Summary:A case of hair depigmentation induced by chloroquine diphosphate subacute overdosage in an 11-year-old patient with dermatomyositis is presented. Normal coloured hair growth occurred after normalisation of chloroquine dosage. A discussion on possible pathomechanisms of this phenomenon is made based on experimental data and previously reported patients with the same condition.
ISSN:0961-2033
1477-0962
DOI:10.1177/0961203308097473