Moderate consumption of a soluble green/roasted coffee rich in caffeoylquinic acids reduces cardiovascular risk markers: results from a randomized, cross-over, controlled trial in healthy and hypercholesterolemic subjects

Purpose Coffee is rich in bioactive compounds with health beneficial properties, with green coffee presenting higher phenol content than roasted. We evaluated the effects of regularly consuming realistic amounts of a green/roasted coffee blend on cardiovascular health-related biomarkers. Methods A r...

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Bibliographic Details
Published in:European journal of nutrition 2019-03, Vol.58 (2), p.865-878
Main Authors: Martínez-López, Sara, Sarriá, Beatriz, Mateos, R., Bravo-Clemente, Laura
Format: Article
Language:English
Subjects:
Adolescent
Adult
Antioxidants
Beans
Bioactive compounds
Biomarkers - blood
Blood pressure
Body weight
C-reactive protein
Cardiovascular diseases
Cardiovascular Diseases - blood
Chemistry
Chemistry and Materials Science
Chemokines
Cholesterol
Clinical trials
Coffee
Coffee - metabolism
Cross-Over Studies
Diet - methods
Evidence-based medicine
Female
Granulocyte colony-stimulating factor
Granulocyte-macrophage colony-stimulating factor
Heart rate
Humans
Hypercholesterolemia - blood
Interleukin 10
Interleukin 12
Interleukin 13
Interleukin 17
Interleukin 2
Interleukin 4
Interleukin 5
Interleukin 6
Interleukin 7
Lipids
Male
Middle Aged
Monocyte chemoattractant protein 1
Nutrition
Original Contribution
Oxidation
Plasma
Quinic Acid - analogs & derivatives
Quinic Acid - blood
Quinic Acid - metabolism
Quinic Acid - pharmacology
Risk Factors
Triglycerides
Young Adult
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Summary:Purpose Coffee is rich in bioactive compounds with health beneficial properties, with green coffee presenting higher phenol content than roasted. We evaluated the effects of regularly consuming realistic amounts of a green/roasted coffee blend on cardiovascular health-related biomarkers. Methods A randomized, cross-over, controlled study was carried out in 25 normocholesterolemic [total cholesterol (TC) 
ISSN:1436-6207
1436-6215
DOI:10.1007/s00394-018-1726-x