Paradoxical psoriasis following anti–TNF therapy in ankylosing spondylitis: A population-based cohort study

[...]we did not evaluate some variables that may contribute to the development of psoriasiform disease including smoking status and obesity. [...]patients with AS with higher disease activity could be assigned to the group treated with anti–TNF-α agents, and we cannot exclude the possibility that th...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2018-09, Vol.142 (3), p.1001-1003.e2
Main Authors: Bae, Jung Min, Kwon, Hyuck Sun, Kim, Gyong Moon, Park, Kyung-Su, Kim, Ki-Jo
Format: Article
Language:English
Subjects:
Age
Ankylosing spondylitis
Females
Males
Nonsteroidal anti-inflammatory drugs
Population
Population studies
Psoriasis
Skin diseases
Spondylitis
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Summary:[...]we did not evaluate some variables that may contribute to the development of psoriasiform disease including smoking status and obesity. [...]patients with AS with higher disease activity could be assigned to the group treated with anti–TNF-α agents, and we cannot exclude the possibility that those patients might be associated more with psoriasis. [...]this study confirmed that the risk of new-onset psoriasis and PPP was significantly increased in patients with AS receiving anti–TNF agents.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2018.05.015