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A novel approach to accurate 3D high resolution and high SNR fetal brain imaging
Fetal brain imaging by MRI is attracting increasing interest because it offers excellent contrast and anatomical details. However, unpredictable fetal motion has led to widespread use of single shot techniques to freeze fetal motion. The conventional result is series of images which have an uncertai...
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creator | Shuzhou Jiang Hui Xue Glover, A. Rutherford, M. Hajnal, J.V. |
description | Fetal brain imaging by MRI is attracting increasing interest because it offers excellent contrast and anatomical details. However, unpredictable fetal motion has led to widespread use of single shot techniques to freeze fetal motion. The conventional result is series of images which have an uncertain spatial relationship and cannot be reconstructed into a coherent 3D volume. We present a novel methodology to reconstruct 3D images of fetal brains in-utero with sub-millimeter isotropic high resolution and high SNR. After continuous scanning to acquire a repeated series of parallel slices, image registration is used to realign the images to correct for fetal motion. Compounding of multiple images yields high SNR even with imaging parameters chosen to provide high resolution at the expense of SNR in individual images. The method has been tested on four normal fetuses imaged at 1.5 T and validated on both adult and neonatal simulated data. In all cases detailed 3D brain images with anatomical details clearly visible in all planes were successfully reconstructed |
doi_str_mv | 10.1109/ISBI.2006.1625003 |
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In all cases detailed 3D brain images with anatomical details clearly visible in all planes were successfully reconstructed</description><subject>Brain</subject><subject>High-resolution imaging</subject><subject>Image reconstruction</subject><subject>Image registration</subject><subject>Image resolution</subject><subject>Magnetic resonance imaging</subject><subject>Optical imaging</subject><subject>Pediatrics</subject><subject>Spatial resolution</subject><subject>Testing</subject><issn>1945-7928</issn><issn>1945-8452</issn><isbn>078039576X</isbn><isbn>9780780395763</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2006</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><recordid>eNotkMtOwzAQRS0eEqX0AxAbr9iljN_2srQ8KlWAaBfsIsd2WqM0KXGCxN8Tqb2bkWaORkcXoVsCU0LAPCzXj8spBZBTIqkAYGdoRAwXmeaCnqNrUBqYEUp-XZwOylB9hSYpfcMQxTkDPkIfM1w3v6HC9nBoG-t2uGuwda5vbRcwW-Bd3O5wG1JT9V1samxrf9yt3z5xGTpb4aK1scZxb7ex3t6gy9JWKUxOc4w2z0-b-Wu2en9ZzmerzBHNu6z0moH3xEkOfnCWXlKgjlvPCxasKkNhlODKG1GA5waEZsxrL4UWRFg2RvfHt4P1Tx9Sl-9jcqGqbB2aPuUUuJGUsQG8O4IxhJAf2kGz_ctPpbF_hWxcyg</recordid><startdate>2006</startdate><enddate>2006</enddate><creator>Shuzhou Jiang</creator><creator>Hui Xue</creator><creator>Glover, A.</creator><creator>Rutherford, M.</creator><creator>Hajnal, J.V.</creator><general>IEEE</general><scope>6IE</scope><scope>6IL</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIL</scope><scope>7QO</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>2006</creationdate><title>A novel approach to accurate 3D high resolution and high SNR fetal brain imaging</title><author>Shuzhou Jiang ; Hui Xue ; Glover, A. ; Rutherford, M. ; Hajnal, J.V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c184t-fd830dd1c640d8456d6202c4ad4b3ea7feb97547d95b0d4905833d8d658515a3</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Brain</topic><topic>High-resolution imaging</topic><topic>Image reconstruction</topic><topic>Image registration</topic><topic>Image resolution</topic><topic>Magnetic resonance imaging</topic><topic>Optical imaging</topic><topic>Pediatrics</topic><topic>Spatial resolution</topic><topic>Testing</topic><toplevel>online_resources</toplevel><creatorcontrib>Shuzhou Jiang</creatorcontrib><creatorcontrib>Hui Xue</creatorcontrib><creatorcontrib>Glover, A.</creatorcontrib><creatorcontrib>Rutherford, M.</creatorcontrib><creatorcontrib>Hajnal, J.V.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan All Online (POP All Online) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEL</collection><collection>IEEE Proceedings Order Plans (POP All) 1998-Present</collection><collection>Biotechnology Research Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Shuzhou Jiang</au><au>Hui Xue</au><au>Glover, A.</au><au>Rutherford, M.</au><au>Hajnal, J.V.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>A novel approach to accurate 3D high resolution and high SNR fetal brain imaging</atitle><btitle>2006 3rd IEEE International Symposium on Biomedical Imaging--Macro to Nano : Arlington, WA, 6-9 April 2006</btitle><stitle>ISBI</stitle><date>2006</date><risdate>2006</risdate><volume>3</volume><spage>662</spage><epage>665</epage><pages>662-665</pages><issn>1945-7928</issn><eissn>1945-8452</eissn><isbn>078039576X</isbn><isbn>9780780395763</isbn><abstract>Fetal brain imaging by MRI is attracting increasing interest because it offers excellent contrast and anatomical details. However, unpredictable fetal motion has led to widespread use of single shot techniques to freeze fetal motion. The conventional result is series of images which have an uncertain spatial relationship and cannot be reconstructed into a coherent 3D volume. We present a novel methodology to reconstruct 3D images of fetal brains in-utero with sub-millimeter isotropic high resolution and high SNR. After continuous scanning to acquire a repeated series of parallel slices, image registration is used to realign the images to correct for fetal motion. Compounding of multiple images yields high SNR even with imaging parameters chosen to provide high resolution at the expense of SNR in individual images. The method has been tested on four normal fetuses imaged at 1.5 T and validated on both adult and neonatal simulated data. 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identifier | ISSN: 1945-7928 |
ispartof | 2006 3rd IEEE International Symposium on Biomedical Imaging--Macro to Nano : Arlington, WA, 6-9 April 2006, 2006, Vol.3, p.662-665 |
issn | 1945-7928 1945-8452 |
language | eng |
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source | IEEE Electronic Library (IEL) Conference Proceedings |
subjects | Brain High-resolution imaging Image reconstruction Image registration Image resolution Magnetic resonance imaging Optical imaging Pediatrics Spatial resolution Testing |
title | A novel approach to accurate 3D high resolution and high SNR fetal brain imaging |
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