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MUC5AC Levels Associated With Respiratory Syncytial Virus Disease Severity

Abstract To assess MUC5AC as a biomarker for respiratory syncytial virus (RSV) disease severity, we tested nasal aspirates from RSV+ children with mild, moderate, and severe disease. Levels were significantly higher in those in the severe and moderate groups compared to mild group, indicating MUC5AC...

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Bibliographic Details
Published in:Clinical infectious diseases 2018-10, Vol.67 (9), p.1441-1444
Main Authors: Rajan, Devi, O'Keefe, Evan L, Travers, Curtis, McCracken, Courtney, Geoghegan, Sarah, Caballero, Mauricio T, Acosta, Patricio L, Polack, Fernando, Anderson, Larry J
Format: Article
Language:English
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Summary:Abstract To assess MUC5AC as a biomarker for respiratory syncytial virus (RSV) disease severity, we tested nasal aspirates from RSV+ children with mild, moderate, and severe disease. Levels were significantly higher in those in the severe and moderate groups compared to mild group, indicating MUC5AC may be a useful biomarker for RSV disease severity.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciy340