Dietary Exposure to Tebuconazole Affects Testicular and Epididymal Histomorphometry in Frugivorous Bats

This study evaluated the effects of a commercially recommended concentration (1 mL/L) of a fungicide tebuconazole (TBZ) on testicular and epididymal histomorphometry of Artibeus lituratus , following 7 and 30-day oral exposure. TBZ30 bats showed a reduction in the percentage of tubules and seminifer...

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Bibliographic Details
Published in:Bulletin of environmental contamination and toxicology 2018-08, Vol.101 (2), p.197-204
Main Authors: Machado-Neves, Mariana, Neto, Mário J. O., Miranda, Diane C., Souza, Ana Cláudia F., Castro, Mariana M., Sertorio, Marcela N., Carvalho, Túlio F., Matta, Sérgio L. P., Freitas, Mariella B.
Format: Article
Language:English
Subjects:
Animals
Aquatic Pollution
Bats
Blood vessels
Chiroptera
Dietary Exposure - adverse effects
Earth and Environmental Science
Ecotoxicology
Environment
Environmental Chemistry
Environmental Health
Enzymes
Epithelium
Exposure
Fertility
Fruits
Fungi
Fungicides
Fungicides, Industrial - toxicity
Histomorphometry
Leydig cells
Male
Morphometry
Organs
Pesticides
Pollution
Reproduction - drug effects
Soil Science & Conservation
Sperm
Tebuconazole
Testes
Testis - drug effects
Toxicology
Triazoles - toxicity
Tubules
Waste Water Technology
Water Management
Water Pollution Control
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Summary:This study evaluated the effects of a commercially recommended concentration (1 mL/L) of a fungicide tebuconazole (TBZ) on testicular and epididymal histomorphometry of Artibeus lituratus , following 7 and 30-day oral exposure. TBZ30 bats showed a reduction in the percentage of tubules and seminiferous epithelium, as well as a decrease in tubule and epithelium somatic indexes, and tubular diameter. Inversely, these animals showed increased percentage of intertubular compartment, Leydig cells and blood vessels. The volume of Leydig cells and their number per gram of testis also increased in TBZ30 bats. Alterations in epididymal morphometry were observed in all regions of the organ, with increase of ductal diameter in both exposure times. These results indicate that exposure to low concentration of TBZ resulted in testicular and epididymal morphometric changes in fruit bats, mainly at 30-day exposure, suggesting that functional alterations might be occurring in these organs and impacting reproductive capacity.
ISSN:0007-4861
1432-0800
DOI:10.1007/s00128-018-2377-6