Long-term Exposure to Ambient Particulate Matter and Prevalence of Subclinical Atherosclerosis in the Multi-Ethnic Study of Atherosclerosis

Exposure to airborne particulate matter has been linked to cardiovascular events. Whether this finding reflects an effect of particulate matter exposure on the triggering of events or development of atherosclerosis remains unknown. Using data from the Multi-Ethnic Study of Atherosclerosis collected...

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Bibliographic Details
Published in:American journal of epidemiology 2008-03, Vol.167 (6), p.667-675
Main Authors: Diez Roux, Ana V., Auchincloss, Amy H., Franklin, Tracy Green, Raghunathan, Trivellore, Barr, R. Graham, Kaufman, Joel, Astor, Brad, Keeler, Jerry
Format: Article
Language:English
Subjects:
Adolescent
Adult
Airborne particulates
Analysis. Health state
atherosclerosis
Atherosclerosis (general aspects, experimental research)
Biological and medical sciences
Blood and lymphatic vessels
Body Mass Index
Cardiology. Vascular system
Cardiovascular disease
cardiovascular diseases
carotid artery diseases
Carotid Artery Diseases - diagnosis
Carotid Artery Diseases - epidemiology
Carotid Artery Diseases - ethnology
Environment. Living conditions
environmental exposure
Environmental Exposure - adverse effects
Epidemiology
Ethnic Groups
Female
General aspects
Health Status
Humans
Male
Medical research
Medical sciences
Michigan - epidemiology
Middle Aged
Motor Activity
particulate matter
Particulate Matter - adverse effects
Prevalence
Public health. Hygiene
Public health. Hygiene-occupational medicine
Socioeconomic Factors
Time Factors
Vein & artery diseases
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Summary:Exposure to airborne particulate matter has been linked to cardiovascular events. Whether this finding reflects an effect of particulate matter exposure on the triggering of events or development of atherosclerosis remains unknown. Using data from the Multi-Ethnic Study of Atherosclerosis collected at baseline (2000–2002), the authors investigated associations of 20-year exposures to particulate matter with measures of subclinical disease (coronary calcium, common carotid intimal-medial thickness, and ankle-brachial index) in 5,172 US adults without clinical cardiovascular disease. Particulate matter exposures for the 20 years prior to assessment of subclinical disease were obtained from a space-time model of Environmental Protection Agency monitor data linked to residential history data for each participant. Intimal-medial thickness was weakly, positively associated with exposures to particulate matter
ISSN:0002-9262
1476-6256
DOI:10.1093/aje/kwm359