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Mid-term 4-Year Outcomes with Single Anastomosis Duodenal-Ileal Bypass with Sleeve Gastrectomy Surgery at a Single US Center

Background Single anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) is a modification of Roux-en-Y duodenal switch (RYDS). Long-term data on this operation is lacking in the literature. We reviewed our mid-term data of this RYDS modification. Purpose To analyze the outcomes with SAD...

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Published in:Obesity surgery 2018-10, Vol.28 (10), p.3062-3072
Main Authors: Zaveri, Hinali, Surve, Amit, Cottam, Daniel, Cottam, Austin, Medlin, Walter, Richards, Christina, Belnap, LeGrand, Cottam, Samuel, Horsley, Benjamin
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container_issue 10
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container_title Obesity surgery
container_volume 28
creator Zaveri, Hinali
Surve, Amit
Cottam, Daniel
Cottam, Austin
Medlin, Walter
Richards, Christina
Belnap, LeGrand
Cottam, Samuel
Horsley, Benjamin
description Background Single anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) is a modification of Roux-en-Y duodenal switch (RYDS). Long-term data on this operation is lacking in the literature. We reviewed our mid-term data of this RYDS modification. Purpose To analyze the outcomes with SADI-S at 4 years. Methods Data from patients who underwent a primary SADI-S procedure performed by three surgeons at a single institution from June 2013 through February 2018 were retrospectively reviewed. All revision bariatric surgeries were excluded. Regression analyses were performed for all follow-up weight loss data. Results There were 437 patients in our database. The pre-operative mean body mass index (BMI) was 49.8 ± 8.8 kg/m 2 . The 30-day complication rate was 7.7%. The 30-day readmission, reoperation, and mortality rates were 1.8, 1.3, and 0.2%, respectively. The long-term complication rate was 10.9%. Seventy-nine patients were 4 years post SADI-S surgery and follow-up was possible for 44 patients (55.7%). At 4 years, patients had an average change in BMI of 18.1 ± 6 units with an excess weight loss (EWL) of 85.7 ± 27.3%. At 4 years, 97.6% patients were able to maintain HbA1c 
doi_str_mv 10.1007/s11695-018-3358-x
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Long-term data on this operation is lacking in the literature. We reviewed our mid-term data of this RYDS modification. Purpose To analyze the outcomes with SADI-S at 4 years. Methods Data from patients who underwent a primary SADI-S procedure performed by three surgeons at a single institution from June 2013 through February 2018 were retrospectively reviewed. All revision bariatric surgeries were excluded. Regression analyses were performed for all follow-up weight loss data. Results There were 437 patients in our database. The pre-operative mean body mass index (BMI) was 49.8 ± 8.8 kg/m 2 . The 30-day complication rate was 7.7%. The 30-day readmission, reoperation, and mortality rates were 1.8, 1.3, and 0.2%, respectively. The long-term complication rate was 10.9%. Seventy-nine patients were 4 years post SADI-S surgery and follow-up was possible for 44 patients (55.7%). At 4 years, patients had an average change in BMI of 18.1 ± 6 units with an excess weight loss (EWL) of 85.7 ± 27.3%. At 4 years, 97.6% patients were able to maintain HbA1c &lt; 6% with or without the use of diabetic medication. There was a statistically significant difference between most of the pre-operative and post-operative nutritional data. Conclusions SADI-S is a safe and effective procedure in both short- and mid-term data points. Diabetes resolution and weight loss appear similar to traditional RYDS and better than RYGB.</description><identifier>ISSN: 0960-8923</identifier><identifier>EISSN: 1708-0428</identifier><identifier>DOI: 10.1007/s11695-018-3358-x</identifier><identifier>PMID: 29909514</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Gastrointestinal surgery ; Medicine ; Medicine &amp; Public Health ; Obesity ; Original Contributions ; Surgery ; Surgical outcomes ; Surgical techniques</subject><ispartof>Obesity surgery, 2018-10, Vol.28 (10), p.3062-3072</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2018</rights><rights>Obesity Surgery is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-c66debe37f8514c7c6fc01aa362eab38a0ba1b30b98927dde7472f8eb08d87553</citedby><cites>FETCH-LOGICAL-c372t-c66debe37f8514c7c6fc01aa362eab38a0ba1b30b98927dde7472f8eb08d87553</cites><orcidid>0000-0001-8830-0291</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29909514$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zaveri, Hinali</creatorcontrib><creatorcontrib>Surve, Amit</creatorcontrib><creatorcontrib>Cottam, Daniel</creatorcontrib><creatorcontrib>Cottam, Austin</creatorcontrib><creatorcontrib>Medlin, Walter</creatorcontrib><creatorcontrib>Richards, Christina</creatorcontrib><creatorcontrib>Belnap, LeGrand</creatorcontrib><creatorcontrib>Cottam, Samuel</creatorcontrib><creatorcontrib>Horsley, Benjamin</creatorcontrib><title>Mid-term 4-Year Outcomes with Single Anastomosis Duodenal-Ileal Bypass with Sleeve Gastrectomy Surgery at a Single US Center</title><title>Obesity surgery</title><addtitle>OBES SURG</addtitle><addtitle>Obes Surg</addtitle><description>Background Single anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) is a modification of Roux-en-Y duodenal switch (RYDS). Long-term data on this operation is lacking in the literature. We reviewed our mid-term data of this RYDS modification. Purpose To analyze the outcomes with SADI-S at 4 years. Methods Data from patients who underwent a primary SADI-S procedure performed by three surgeons at a single institution from June 2013 through February 2018 were retrospectively reviewed. All revision bariatric surgeries were excluded. Regression analyses were performed for all follow-up weight loss data. Results There were 437 patients in our database. The pre-operative mean body mass index (BMI) was 49.8 ± 8.8 kg/m 2 . The 30-day complication rate was 7.7%. The 30-day readmission, reoperation, and mortality rates were 1.8, 1.3, and 0.2%, respectively. The long-term complication rate was 10.9%. Seventy-nine patients were 4 years post SADI-S surgery and follow-up was possible for 44 patients (55.7%). At 4 years, patients had an average change in BMI of 18.1 ± 6 units with an excess weight loss (EWL) of 85.7 ± 27.3%. At 4 years, 97.6% patients were able to maintain HbA1c &lt; 6% with or without the use of diabetic medication. There was a statistically significant difference between most of the pre-operative and post-operative nutritional data. Conclusions SADI-S is a safe and effective procedure in both short- and mid-term data points. 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Long-term data on this operation is lacking in the literature. We reviewed our mid-term data of this RYDS modification. Purpose To analyze the outcomes with SADI-S at 4 years. Methods Data from patients who underwent a primary SADI-S procedure performed by three surgeons at a single institution from June 2013 through February 2018 were retrospectively reviewed. All revision bariatric surgeries were excluded. Regression analyses were performed for all follow-up weight loss data. Results There were 437 patients in our database. The pre-operative mean body mass index (BMI) was 49.8 ± 8.8 kg/m 2 . The 30-day complication rate was 7.7%. The 30-day readmission, reoperation, and mortality rates were 1.8, 1.3, and 0.2%, respectively. The long-term complication rate was 10.9%. Seventy-nine patients were 4 years post SADI-S surgery and follow-up was possible for 44 patients (55.7%). 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subjects Gastrointestinal surgery
Medicine
Medicine & Public Health
Obesity
Original Contributions
Surgery
Surgical outcomes
Surgical techniques
title Mid-term 4-Year Outcomes with Single Anastomosis Duodenal-Ileal Bypass with Sleeve Gastrectomy Surgery at a Single US Center
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