Imaging of Chemokine Receptor CXCR4 in Mycosis Fungoides Using 68Ga-Pentixafor PET/CT

ABSTRACTA 52-year-old woman diagnosed with mycosis fungoides was referred for F-FDG PET/CT before treatment for the evaluation of disease severity. The patient also underwent Ga-pentixafor PET/CT for further evaluation. FDG uptake was observed in cervical, axillary, and pelvic lymph nodes and multip...

Full description

Saved in:
Bibliographic Details
Published in:Clinical nuclear medicine 2018-08, Vol.43 (8), p.606-608
Main Authors: Kuyumcu, Serkan, Yilmaz, Ebru, Büyükkaya, Fikret, Özkan, Zeynep Gözde, Ünal, Seher Nilgün
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ABSTRACTA 52-year-old woman diagnosed with mycosis fungoides was referred for F-FDG PET/CT before treatment for the evaluation of disease severity. The patient also underwent Ga-pentixafor PET/CT for further evaluation. FDG uptake was observed in cervical, axillary, and pelvic lymph nodes and multiple widespread skin lesions throughout the body, suggestive of extensive involvement of mycosis fungoides. All lesions were visually identifiable with high target-to-background ratio on Ga-pentixafor PET/CT which demonstrated marked CXCR4 expression in all lesions that were detected using F-FDG PET/CT.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000002166