Complete mitogenome reveals genetic divergence and phylogenetic relationships among Indian cattle (Bos indicus) breeds

Indigenous cattle of India belong to the species, Bos indicus and they possess various adaptability and production traits. However, little is known about the genetic diversity and origin of these breeds. To investigate the status, we sequenced and analyzed the whole mitochondrial DNA (mtDNA) of seve...

Full description

Saved in:
Bibliographic Details
Published in:Animal biotechnology 2019-07, Vol.30 (3), p.219-232
Main Authors: Pramod, R. Kumar, Velayutham, Dinesh, P. K., Sajesh, P. S., Beena, Zachariah, Anil, Zachariah, Arun, B., Chandramohan, S. S., Sujith, P., Ganapathi, Dhinoth Kumar, Bangarusamy, Iype, Sosamma, Gupta, Ravi, Santhosh, Sam, Thomas, George
Format: Article
Language:English
Subjects:
Adaptability
Bos indicus
Bos taurus
Bovidae
Cattle
COII gene
Deoxyribonucleic acid
Divergence
DNA
Genetic analysis
Genetic distance
genetic divergence
Genetic diversity
Genetic relationship
Genetic variance
Indigenous animals
Mitochondrial DNA
Nucleotide sequence
Phylogenetics
Phylogeny
single-nucleotide variant
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Indigenous cattle of India belong to the species, Bos indicus and they possess various adaptability and production traits. However, little is known about the genetic diversity and origin of these breeds. To investigate the status, we sequenced and analyzed the whole mitochondrial DNA (mtDNA) of seven Indian cattle breeds. In total, 49 single-nucleotide variants (SNVs) were identified among the seven breeds analyzed. We observed a common synonymous SNV in the COII gene (m.7583G > A) of all the breeds studied. The phylogenetic analysis and genetic distance estimation showed the close genetic relationship among the Indian cattle breeds, whereas distinct genetic differences were observed between Bos indicus and Bos taurus cattle. Our results indicate a common ancestor for European Zwergzebu breed and South Indian cattle. The estimated divergence time demonstrated that the Bos indicus and Bos taurus cattle lineages diverged 0.92 million years ago. Our study also demonstrates that ancestors of present zebu breeds originated in South and North India separately ∼30,000 to 20,000 years ago. In conclusion, the identified genetic variants and results of the phylogenetic analysis may provide baseline information to develop appropriate strategies for management and conservation of Indian cattle breeds.
ISSN:1049-5398
1532-2378
DOI:10.1080/10495398.2018.1476376