Ventilation inhomogeneity and NO and CO diffusing capacity in ex-premature school children

Ex-premature school children show mild-to-moderate airway obstruction and decreased CO diffusing capacity. Multiple breath nitrogen washout (N2MBW) and NO diffusing capacity (DLNO) measurements may provide new insight into long-term pulmonary and vascular impairment in bronchopulmonary dysplasia (BP...

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Bibliographic Details
Published in:Respiratory medicine 2018-07, Vol.140, p.94-100
Main Authors: Sørensen, Jesper Kiehn, Buchvald, Frederik, Berg, Anna Korsgaard, Robinson, Paul D., Nielsen, Kim Gjerum
Format: Article
Language:English
Subjects:
Adolescent
Age
Airway management
Birth weight
Birth Weight - physiology
Bronchodilator Agents - therapeutic use
Bronchodilators
Bronchopulmonary dysplasia
Bronchopulmonary Dysplasia - drug therapy
Bronchopulmonary Dysplasia - physiopathology
Carbon Monoxide
Case-Control Studies
Child
Children
Chronic respiratory disease
Correlation analysis
Dysplasia
Electrocardiography
Female
Follow-Up Studies
Gestational Age
Humans
Impairment
Infant, Newborn
Infant, Premature - physiology
Inhomogeneity
Long-term outcome
Longitudinal studies
Lung function
Lungs
Male
Mechanical ventilation
Nitric Oxide
Plethysmography
Premature birth
Premature Birth - physiopathology
Prematurity
Pulmonary Diffusing Capacity - drug effects
Pulmonary Diffusing Capacity - physiology
Questionnaires
Respiratory tract
Software
Spirometry - methods
Ventilation
Ventilators
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Description
Summary:Ex-premature school children show mild-to-moderate airway obstruction and decreased CO diffusing capacity. Multiple breath nitrogen washout (N2MBW) and NO diffusing capacity (DLNO) measurements may provide new insight into long-term pulmonary and vascular impairment in bronchopulmonary dysplasia (BPD). We examined a randomly selected group of 70 ex-premature children (gestational age
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2018.06.006