Diagnosis of Helicobacter pylori infection: A short review

Summary Helicobacter pylori infections represent an important factor in the pathogenesis of chronic gastritis, peptic ulcer, MALT lymphoma and gastric adenocarcinoma. The recently published Maastricht V/Florence consensus report indicated that the urea breath test using 13 C urea still remains the b...

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Published in:Wiener Klinische Wochenschrift 2018-09, Vol.130 (17-18), p.530-534
Main Authors: Tonkic, Ante, Vukovic, Jonatan, Vrebalov Cindro, Pavle, Pesutic Pisac, Valdi, Tonkic, Marija
Format: Article
Language:English
Subjects:
Breath Tests
Endocrinology
Enzyme-Linked Immunosorbent Assay
Feces
Gastroenterology
Helicobacter Infections - diagnosis
Helicobacter pylori
Humans
Internal Medicine
Medicine
Medicine & Public Health
Pneumology/Respiratory System
Review Article
Sensitivity and Specificity
Urea
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creator Tonkic, Ante
Vukovic, Jonatan
Vrebalov Cindro, Pavle
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Tonkic, Marija
description Summary Helicobacter pylori infections represent an important factor in the pathogenesis of chronic gastritis, peptic ulcer, MALT lymphoma and gastric adenocarcinoma. The recently published Maastricht V/Florence consensus report indicated that the urea breath test using 13 C urea still remains the best non-invasive test to diagnose H. pylori infections with high sensitivity and specificity. Among the stool antigen tests, the ELISA monoclonal antibody test is a rational option. Effective therapy should be based only on susceptibility testing in regions with documented high clarithromycin resistance (>15%). Advanced high-resolution endoscopic technologies enable increased diagnostic accuracy for detection of H. pylori infections.
doi_str_mv 10.1007/s00508-018-1356-6
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subjects Breath Tests
Endocrinology
Enzyme-Linked Immunosorbent Assay
Feces
Gastroenterology
Helicobacter Infections - diagnosis
Helicobacter pylori
Humans
Internal Medicine
Medicine
Medicine & Public Health
Pneumology/Respiratory System
Review Article
Sensitivity and Specificity
Urea
title Diagnosis of Helicobacter pylori infection: A short review
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