Antifungal Activity of the Essential Oil of Eugenia Caryophyllata on Candida Albicans, Aspergillus Niger and Aspergillus Flavus

The composition of the essential oil of Eugenia caryophyllata and its antifungal activity on Candida albicans, Aspergillus niger and Aspergillus flavus fungal strains were studied in Iran. Essential oil from the flowers parts of the plant was obtained by hydrodistillation and analysed by GC and GC-M...

Full description

Saved in:
Bibliographic Details
Published in:Biomedical & pharmacology journal 2008-06, Vol.1 (1), p.43-46
Main Authors: Rahimifard, N, Shoeibi, Sh, Pakzad, S R, HajimehdipoOr, H, Sabzevari, O, AjdarY, S
Format: Article
Language:English
Subjects:
Acetic acid
Antifungal activity
Antimicrobial agents
Aspergillus
Aspergillus flavus
Aspergillus niger
Candida albicans
Caryophyllene
Chemical composition
Chromatography
Drugs
Essential oils
Eugenia
Eugenia caryophyllata
Eugenol
Flowers
Fungi
Infections
Mass spectrometry
Minimum inhibitory concentration
Oils & fats
Scientific imaging
Sensors
Temperature
Therapeutic applications
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The composition of the essential oil of Eugenia caryophyllata and its antifungal activity on Candida albicans, Aspergillus niger and Aspergillus flavus fungal strains were studied in Iran. Essential oil from the flowers parts of the plant was obtained by hydrodistillation and analysed by GC and GC-MS. The oil showed high contents of Eugenol, B-caryophyllene and Euggenyl acetate. The MIC was used to evaluate the antifungal activity against Candida albicans ATCC 10231, Aspergillus niger ATCC 9642 and Aspergillus flavus ATCC 9643. Antifungal activity was evaluated for the essential oil and simultaneously for Amphotricin B. Results showed that Eugenia caryophyllata essential oil exhibited a significant activity against fungi, and its MIC on Candida albicans, Aspergillus niger and Aspergillus flavus were respectively 0.50, 0.125 and 0.25 µg ml-1 (ppm).The present study indicates that Eugenia caryophyllata essential oil has considerable antifungal activity, deserving further investigation for clinical applications.
ISSN:0974-6242
2456-2610