Hospitalization Increases the Risk of Acute Arthritic Flares in Gout: A Population-based Study over 2 Decades

To assess in-hospital gout flares in patients with gout. Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010. There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitaliz...

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Bibliographic Details
Published in:Journal of rheumatology 2018-08, Vol.45 (8), p.1188-1191
Main Authors: Zleik, Nour, Elfishawi, Mohanad M, Kvrgic, Zoran, Michet, Jr, Clement J, Crowson, Cynthia S, Matteson, Eric L, Bongartz, Tim
Format: Article
Language:English
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Summary:To assess in-hospital gout flares in patients with gout. Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010. There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989-1992 to 2009-2010 [rate ratio (RR) 1.19, 95% CI 0.98-1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8-14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001). Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.
ISSN:0315-162X
1499-2752
DOI:10.3899/jrheum.171320