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Hypertriglyceridemia is associated with impaired fasting glucose in normal-weight children

Background Previous studies have suggested that elevated triglyceride levels may precede the appearance of glucose metabolic disturbances in adults; nonetheless, this hypothesis has not been tested in children. Hence, we evaluated whether hypertriglyceridemia is associated with impaired fasting gluc...

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Published in:Pediatric research 2018-09, Vol.84 (3), p.352-355
Main Authors: Simental-Mendía, Luis E., Rodríguez-Morán, Martha, Aradillas-García, Celia, Guerrero-Romero, Fernando
Format: Article
Language:English
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Summary:Background Previous studies have suggested that elevated triglyceride levels may precede the appearance of glucose metabolic disturbances in adults; nonetheless, this hypothesis has not been tested in children. Hence, we evaluated whether hypertriglyceridemia is associated with impaired fasting glucose (IFG) in normal-weight children. Methods Normal-weight healthy children aged 7–15 years were enrolled in a population-based cross-sectional population study and allocated into groups with and without hypertriglyceridemia. Hypertriglyceridemia was defined by serum triglyceride levels ≥100 and ≥130 mg/dL for children aged 7–9 and 10–15 years, respectively, and IFG by fasting plasma glucose levels ≥100 and
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-018-0027-7