Consequences of selection in highly inbred Drosophila strains

The results of three long-term breeding and genetic experiments with Drosophila melanogaster performed at different times are summarized. Selections for different fitness components led to similar results. The data on the concentration of viability mutations in the inbred strains LA, LA super(+), an...

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Bibliographic Details
Published in:Russian journal of genetics 2007-10, Vol.43 (10), p.1108-1119
Main Authors: Iovleva, O. V., Mylnikov, S. V.
Format: Article
Language:English
Subjects:
Drosophila melanogaster
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Summary:The results of three long-term breeding and genetic experiments with Drosophila melanogaster performed at different times are summarized. Selections for different fitness components led to similar results. The data on the concentration of viability mutations in the inbred strains LA, LA super(+), and LA super(-) after 400 generations of selection and the strain ULA during its breeding are presented for the first time. The results of studying the genetic heterogeneity and spontaneous mutational process in Drosophila inbred strains comply with the idea of M.E. Lobashev that 'a change in the direction of selection or acceleration of its rate is always accompanied by a concurrent increase in mutational variation.'
ISSN:1022-7954
1608-3369
DOI:10.1134/S1022795407100043