Comparison between radiofrequency ablation and chemical neurolysis of thoracic splanchnic nerves for the management of abdominal cancer pain, randomized trial

Background Radiofrequency ablation (RFA) of the splanchnic nerves has been reported as a predictable and safe technique for abdominal pain management. We compare between RFA and chemical neurolysis of bilateral thoracic splanchnic nerves in the management of refractory cancer pain. Methods The study...

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Bibliographic Details
Published in:European journal of pain 2018-11, Vol.22 (10), p.1782-1790
Main Authors: Amr, S.A., Reyad, R.M., Othman, A.H., Mohamad, M.F., Mostafa, M.M., Alieldin, N.H., Hamed, F.A.
Format: Article
Language:English
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Summary:Background Radiofrequency ablation (RFA) of the splanchnic nerves has been reported as a predictable and safe technique for abdominal pain management. We compare between RFA and chemical neurolysis of bilateral thoracic splanchnic nerves in the management of refractory cancer pain. Methods The study was conducted on 60 patients aged ≥18 years who suffered from abdominal pain (visceral pain, VAS ≥4) due to upper abdominal cancers. Participants were randomized into two groups. Group I (RF): 30 participants received a bilateral splanchnic nerve block at T10 and T11 levels using RFA. Group II (alcohol): 30 participants received a bilateral splanchnic nerve block at T11 using alcohol. Pain relief was assessed using VAS (0–10) and total daily oral opioid consumption (primary outcome). Results Significant reductions of VAS and global perceived effect satisfaction scores (GPES) were observed in both groups compared to baseline levels (p 
ISSN:1090-3801
1532-2149
DOI:10.1002/ejp.1274