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Effects of diacutaneous fibrolysis in patients with mild to moderate symptomatic carpal tunnel syndrome: a randomized controlled trial

Objective: To compare the effects of diacutaneous fibrolysis with sham in patients with mild to moderate carpal tunnel syndrome. Design: Double-blind (patient and evaluator) randomized controlled trial. Setting: Miguel Servet University Hospital, Zaragoza, Spain. Subjects: A total of 52 patients (72...

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Published in:Clinical rehabilitation 2018-12, Vol.32 (12), p.1645-1655
Main Authors: Jiménez del Barrio, Sandra, Estébanez de Miguel, Elena, Bueno Gracia, Elena, Haddad Garay, María, Tricás Moreno, José Miguel, Hidalgo García, César
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container_start_page 1645
container_title Clinical rehabilitation
container_volume 32
creator Jiménez del Barrio, Sandra
Estébanez de Miguel, Elena
Bueno Gracia, Elena
Haddad Garay, María
Tricás Moreno, José Miguel
Hidalgo García, César
description Objective: To compare the effects of diacutaneous fibrolysis with sham in patients with mild to moderate carpal tunnel syndrome. Design: Double-blind (patient and evaluator) randomized controlled trial. Setting: Miguel Servet University Hospital, Zaragoza, Spain. Subjects: A total of 52 patients (72 wrists) with carpal tunnel syndrome, 41 women and 11 men, mean age was 46.9 (8.8) years. They were divided into two groups: diacutaneous fibrolysis group and sham group. Interventions: Real diacutaneous fibrolysis in diacutaneous fibrolysis group and sham diacutaneous fibrolysis in sham group. Both groups received five sessions in the forearm, wrist and hand. Main measures: Neurophysiological parameters assessed at baseline and at the end of the treatment. Intensity of nocturnal symptoms (visual analogue scale (VAS)) and upper limb functional capacity (Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire) at baseline, at the end of the treatment and one month after treatment. Results: Diacutaneous fibrolysis group (n = 30 wrists) improved in nerve conduction distal motor latency (mean difference: –0.26, 95% confidence interval (CI): –0.49/–0.26), sensory conduction velocity (mean difference: 6.52, 95% CI: 3.52/9.51), intensity of nocturnal symptoms (mean difference: –2.24, 95% CI: –4.08/–2.04) and upper limb functional capacity (mean difference: –19, 95% CI: –26.1/–11.9) compared to the sham group (n = 30 wrists) (P 
doi_str_mv 10.1177/0269215518787316
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Design: Double-blind (patient and evaluator) randomized controlled trial. Setting: Miguel Servet University Hospital, Zaragoza, Spain. Subjects: A total of 52 patients (72 wrists) with carpal tunnel syndrome, 41 women and 11 men, mean age was 46.9 (8.8) years. They were divided into two groups: diacutaneous fibrolysis group and sham group. Interventions: Real diacutaneous fibrolysis in diacutaneous fibrolysis group and sham diacutaneous fibrolysis in sham group. Both groups received five sessions in the forearm, wrist and hand. Main measures: Neurophysiological parameters assessed at baseline and at the end of the treatment. Intensity of nocturnal symptoms (visual analogue scale (VAS)) and upper limb functional capacity (Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire) at baseline, at the end of the treatment and one month after treatment. Results: Diacutaneous fibrolysis group (n = 30 wrists) improved in nerve conduction distal motor latency (mean difference: –0.26, 95% confidence interval (CI): –0.49/–0.26), sensory conduction velocity (mean difference: 6.52, 95% CI: 3.52/9.51), intensity of nocturnal symptoms (mean difference: –2.24, 95% CI: –4.08/–2.04) and upper limb functional capacity (mean difference: –19, 95% CI: –26.1/–11.9) compared to the sham group (n = 30 wrists) (P &lt; 0.02, P &lt; 0.01, P &lt; 0.01 and P &lt; 0.01, respectively). At one-month follow-up, improvements in the nocturnal symptoms and upper limb functional capacity were maintained compared to the sham group (P &lt; 0.01). Conclusion: Diacutaneous fibrolysis provides short-term and one-month follow-up, improvements in sensory conduction velocity, motor distal latency, symptoms and functional capacity in patients with mild to moderate carpal tunnel syndrome.</description><identifier>ISSN: 0269-2155</identifier><identifier>EISSN: 1477-0873</identifier><identifier>DOI: 10.1177/0269215518787316</identifier><identifier>PMID: 29991270</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adult ; Carpal tunnel syndrome ; Carpal Tunnel Syndrome - complications ; Carpal Tunnel Syndrome - physiopathology ; Carpal Tunnel Syndrome - rehabilitation ; Clinical trials ; Confidence intervals ; Double-Blind Method ; Evidence-based medicine ; Female ; Functional status ; Humans ; Latency ; Male ; Massage - methods ; Middle Aged ; Neural Conduction ; Physical therapy ; Questionnaires ; Recovery of Function ; Repetitive strain injuries ; Symptom Assessment ; Treatment Outcome ; Wrists</subject><ispartof>Clinical rehabilitation, 2018-12, Vol.32 (12), p.1645-1655</ispartof><rights>The Author(s) 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c407t-344db3a6eb537e7882b25dd7448a6b1b6d8dbc655e40c08ebae1fe745a1ab9613</citedby><cites>FETCH-LOGICAL-c407t-344db3a6eb537e7882b25dd7448a6b1b6d8dbc655e40c08ebae1fe745a1ab9613</cites><orcidid>0000-0002-7460-3061</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925,30999,79364</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29991270$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jiménez del Barrio, Sandra</creatorcontrib><creatorcontrib>Estébanez de Miguel, Elena</creatorcontrib><creatorcontrib>Bueno Gracia, Elena</creatorcontrib><creatorcontrib>Haddad Garay, María</creatorcontrib><creatorcontrib>Tricás Moreno, José Miguel</creatorcontrib><creatorcontrib>Hidalgo García, César</creatorcontrib><title>Effects of diacutaneous fibrolysis in patients with mild to moderate symptomatic carpal tunnel syndrome: a randomized controlled trial</title><title>Clinical rehabilitation</title><addtitle>Clin Rehabil</addtitle><description>Objective: To compare the effects of diacutaneous fibrolysis with sham in patients with mild to moderate carpal tunnel syndrome. Design: Double-blind (patient and evaluator) randomized controlled trial. Setting: Miguel Servet University Hospital, Zaragoza, Spain. Subjects: A total of 52 patients (72 wrists) with carpal tunnel syndrome, 41 women and 11 men, mean age was 46.9 (8.8) years. They were divided into two groups: diacutaneous fibrolysis group and sham group. Interventions: Real diacutaneous fibrolysis in diacutaneous fibrolysis group and sham diacutaneous fibrolysis in sham group. Both groups received five sessions in the forearm, wrist and hand. Main measures: Neurophysiological parameters assessed at baseline and at the end of the treatment. Intensity of nocturnal symptoms (visual analogue scale (VAS)) and upper limb functional capacity (Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire) at baseline, at the end of the treatment and one month after treatment. Results: Diacutaneous fibrolysis group (n = 30 wrists) improved in nerve conduction distal motor latency (mean difference: –0.26, 95% confidence interval (CI): –0.49/–0.26), sensory conduction velocity (mean difference: 6.52, 95% CI: 3.52/9.51), intensity of nocturnal symptoms (mean difference: –2.24, 95% CI: –4.08/–2.04) and upper limb functional capacity (mean difference: –19, 95% CI: –26.1/–11.9) compared to the sham group (n = 30 wrists) (P &lt; 0.02, P &lt; 0.01, P &lt; 0.01 and P &lt; 0.01, respectively). At one-month follow-up, improvements in the nocturnal symptoms and upper limb functional capacity were maintained compared to the sham group (P &lt; 0.01). 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Abstracts (ASSIA)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jiménez del Barrio, Sandra</au><au>Estébanez de Miguel, Elena</au><au>Bueno Gracia, Elena</au><au>Haddad Garay, María</au><au>Tricás Moreno, José Miguel</au><au>Hidalgo García, César</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of diacutaneous fibrolysis in patients with mild to moderate symptomatic carpal tunnel syndrome: a randomized controlled trial</atitle><jtitle>Clinical rehabilitation</jtitle><addtitle>Clin Rehabil</addtitle><date>2018-12</date><risdate>2018</risdate><volume>32</volume><issue>12</issue><spage>1645</spage><epage>1655</epage><pages>1645-1655</pages><issn>0269-2155</issn><eissn>1477-0873</eissn><abstract>Objective: To compare the effects of diacutaneous fibrolysis with sham in patients with mild to moderate carpal tunnel syndrome. Design: Double-blind (patient and evaluator) randomized controlled trial. Setting: Miguel Servet University Hospital, Zaragoza, Spain. Subjects: A total of 52 patients (72 wrists) with carpal tunnel syndrome, 41 women and 11 men, mean age was 46.9 (8.8) years. They were divided into two groups: diacutaneous fibrolysis group and sham group. Interventions: Real diacutaneous fibrolysis in diacutaneous fibrolysis group and sham diacutaneous fibrolysis in sham group. Both groups received five sessions in the forearm, wrist and hand. Main measures: Neurophysiological parameters assessed at baseline and at the end of the treatment. Intensity of nocturnal symptoms (visual analogue scale (VAS)) and upper limb functional capacity (Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire) at baseline, at the end of the treatment and one month after treatment. Results: Diacutaneous fibrolysis group (n = 30 wrists) improved in nerve conduction distal motor latency (mean difference: –0.26, 95% confidence interval (CI): –0.49/–0.26), sensory conduction velocity (mean difference: 6.52, 95% CI: 3.52/9.51), intensity of nocturnal symptoms (mean difference: –2.24, 95% CI: –4.08/–2.04) and upper limb functional capacity (mean difference: –19, 95% CI: –26.1/–11.9) compared to the sham group (n = 30 wrists) (P &lt; 0.02, P &lt; 0.01, P &lt; 0.01 and P &lt; 0.01, respectively). At one-month follow-up, improvements in the nocturnal symptoms and upper limb functional capacity were maintained compared to the sham group (P &lt; 0.01). Conclusion: Diacutaneous fibrolysis provides short-term and one-month follow-up, improvements in sensory conduction velocity, motor distal latency, symptoms and functional capacity in patients with mild to moderate carpal tunnel syndrome.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>29991270</pmid><doi>10.1177/0269215518787316</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-7460-3061</orcidid><oa>free_for_read</oa></addata></record>
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source Applied Social Sciences Index & Abstracts (ASSIA); SAGE Journals
subjects Adult
Carpal tunnel syndrome
Carpal Tunnel Syndrome - complications
Carpal Tunnel Syndrome - physiopathology
Carpal Tunnel Syndrome - rehabilitation
Clinical trials
Confidence intervals
Double-Blind Method
Evidence-based medicine
Female
Functional status
Humans
Latency
Male
Massage - methods
Middle Aged
Neural Conduction
Physical therapy
Questionnaires
Recovery of Function
Repetitive strain injuries
Symptom Assessment
Treatment Outcome
Wrists
title Effects of diacutaneous fibrolysis in patients with mild to moderate symptomatic carpal tunnel syndrome: a randomized controlled trial
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