Factors associated with a prolonged hospital stay during induction chemotherapy in newly diagnosed high risk pediatric acute lymphoblastic leukemia

•High risk ALL patients experience significant adverse events during induction.•Factors predictive of prolonged hospital stay during induction were identified.•Outpatient management of new ALL patients is often not feasible or safe.•An aggressive and close outpatient follow up of these patients is i...

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Bibliographic Details
Published in:Leukemia research 2018-08, Vol.71, p.36-42
Main Authors: Warrick, Kasper, Althouse, Sandra K., Rahrig, April, Rupenthal, Joy, Batra, Sandeep
Format: Article
Language:English
Subjects:
Length-of-stay
Leukemia
Pediatric
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Summary:•High risk ALL patients experience significant adverse events during induction.•Factors predictive of prolonged hospital stay during induction were identified.•Outpatient management of new ALL patients is often not feasible or safe.•An aggressive and close outpatient follow up of these patients is indicated. High Risk (HR) or Very High Risk (VHR) acute lymphoblastic leukemia (ALL) treated with 4 drug induction chemotherapy is often associated with adverse events. The aim of this study was to identify risk factors associated with a prolonged inpatient length of stay LOS during induction chemotherapy. Data from patients (N = 73) (age
ISSN:0145-2126
1873-5835
DOI:10.1016/j.leukres.2018.06.013