Catheter ablation of atrial fibrillation with heart failure: An updated meta-analysis of randomized trials

Atrial fibrillation (AF) and heart failure (HF) often coexist. We conducted this meta-analysis to assess the efficacy and safety of catheter ablation in this population. Electronic databases were searched for all randomized clinical trials (RCTs) that evaluated catheter ablation in patients with lef...

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Bibliographic Details
Published in:International journal of cardiology 2018-10, Vol.269, p.170-173
Main Authors: Kheiri, Babikir, Osman, Mohammed, Abdalla, Ahmed, Haykal, Tarek, Ahmed, Sahar, Bachuwa, Ghassan, Hassan, Mustafa, Bhatt, Deepak L.
Format: Article
Language:English
Subjects:
Atrial fibrillation
Atrial Fibrillation - epidemiology
Atrial Fibrillation - physiopathology
Atrial Fibrillation - surgery
Catheter ablation
Catheter Ablation - methods
Catheter Ablation - trends
Heart failure
Heart Failure - epidemiology
Heart Failure - physiopathology
Heart Failure - surgery
Hospitalization - trends
Humans
Meta-analysis
Randomized Controlled Trials as Topic - methods
Systolic dysfunction
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Summary:Atrial fibrillation (AF) and heart failure (HF) often coexist. We conducted this meta-analysis to assess the efficacy and safety of catheter ablation in this population. Electronic databases were searched for all randomized clinical trials (RCTs) that evaluated catheter ablation in patients with left ventricular systolic dysfunction (LVSD). We calculated the weighted mean differences (MDs) and risk ratios (RRs) using a random-effects model. We included 7 RCTs with 851 patients (mean follow-up was 18 months). Catheter ablation in patients with LVSD was associated with significantly lower HF hospitalization rates (RR 0.57; 95% CI: 0.45–0.72; P 
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2018.07.024