Relationship between resting heart rate and metabolic risk factors in breast cancer patients

Higher resting heart rate (RHR) was associated with poor prognosis in breast cancer survivors, but the mechanism underlying such association has not been fully studied. We investigated the association between RHR and metabolic risk factors in stage I-III breast cancer survivors. Among 11,013 women d...

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Bibliographic Details
Published in:Clinica chimica acta 2018-11, Vol.486, p.104-109
Main Authors: Lee, Mi Kyung, Lee, Dong Hoon, Park, Seho, Kim, Seung Il, Jeon, Justin Y.
Format: Article
Language:English
Subjects:
Breast cancer survivors
Breast Neoplasms - blood
Breast Neoplasms - diagnosis
Breast Neoplasms - metabolism
Cancer Survivors
Cholesterol - blood
Female
Heart Rate
Humans
Metabolic risk factor
Middle Aged
Neoplasm Staging
Prognosis
Republic of Korea
Rest
Resting heart rate
Risk Factors
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Summary:Higher resting heart rate (RHR) was associated with poor prognosis in breast cancer survivors, but the mechanism underlying such association has not been fully studied. We investigated the association between RHR and metabolic risk factors in stage I-III breast cancer survivors. Among 11,013 women diagnosed with breast cancer between 2005 and 2013 at the Severance hospital in Seoul, Korea, a total of 4980 patients met our inclusion criteria for the final analysis. Multivariable linear regressions were used to examine the association between RHR and metabolic risk factors, including systolic blood pressure (SBP), diastolic blood pressure (DBP), glucose, triglyceride (TG), total cholesterol, high density lipid cholesterol (HDLC), and low density lipid cholesterol. The results showed that RHR had significant linear associations with SBP (p = .02), DBP (p 
ISSN:0009-8981
1873-3492
DOI:10.1016/j.cca.2018.07.032