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Multi-organ toxicity and death following acute unintentional inhalation of paint thinner fumes
Paint thinners containing a mixture of volatile organic solvents have considerable potential for solvent abuse. Deaths from solvent inhalation have been reported but most of them relate to intentional solvent abuse and occur soon after exposure. Accidental death due to unintentional inhalation of so...
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| Published in: | Clinical toxicology (Philadelphia, Pa.) Pa.), 2007-01, Vol.45 (3), p.287-289 |
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| Main Authors: | , , , , , , , , |
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| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c509t-b7bed3c5e7e63f9a7c01433916dfd8fedee2101be68acfdc6a8c20eb56f2f6d03 |
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| cites | cdi_FETCH-LOGICAL-c509t-b7bed3c5e7e63f9a7c01433916dfd8fedee2101be68acfdc6a8c20eb56f2f6d03 |
| container_end_page | 289 |
| container_issue | 3 |
| container_start_page | 287 |
| container_title | Clinical toxicology (Philadelphia, Pa.) |
| container_volume | 45 |
| creator | ZAIDI, Shakeel A SHAW, Asha N PATEL, Monila N SHAH, Vipul V RAJENDRAN, Dipa SHAH, Bhaumik P SINHA, Sukesh N GANDHI, Sumitra J SAIYED, Habibullah N |
| description | Paint thinners containing a mixture of volatile organic solvents have considerable potential for solvent abuse. Deaths from solvent inhalation have been reported but most of them relate to intentional solvent abuse and occur soon after exposure. Accidental death due to unintentional inhalation of solvent vapors can also occur suddenly but more often, death results from late complications secondary to multi-organ toxicity. Malfunctioning of the cardiorespiratory, renal, and central nervous systems as a result of latent-toxic effects of solvent exposure has received little attention.
An adult male unintentionally inhaled an excessive amount of paint thinner vapors and immediately developed central nervous system effects, followed by severe cardiorespiratory and renal pathologies that ultimately led to death 11 days after exposure.
Acute unintentional inhalation of paint thinner fumes resulted in serious multi-organ toxicity and death. This case strongly suggests the need to employ suitable precautionary measures while handling volatile organic solvents in a confined area. |
| doi_str_mv | 10.1080/15563650601031791 |
| format | article |
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An adult male unintentionally inhaled an excessive amount of paint thinner vapors and immediately developed central nervous system effects, followed by severe cardiorespiratory and renal pathologies that ultimately led to death 11 days after exposure.
Acute unintentional inhalation of paint thinner fumes resulted in serious multi-organ toxicity and death. This case strongly suggests the need to employ suitable precautionary measures while handling volatile organic solvents in a confined area.</description><identifier>ISSN: 1556-3650</identifier><identifier>EISSN: 1556-9519</identifier><identifier>DOI: 10.1080/15563650601031791</identifier><identifier>PMID: 17453883</identifier><language>eng</language><publisher>Philadelphia, PA: Taylor & Francis</publisher><subject>Adolescent ; Air Pollutants - poisoning ; Biological and medical sciences ; Brain Diseases, Metabolic - chemically induced ; Brain Diseases, Metabolic - pathology ; Cardiovascular Diseases - chemically induced ; Cardiovascular Diseases - pathology ; Chemical and industrial products toxicology. Toxic occupational diseases ; Fatal Outcome ; Gas Chromatography-Mass Spectrometry ; Humans ; Inhalation Exposure - adverse effects ; Kidney Diseases - chemically induced ; Kidney Diseases - pathology ; Lung Diseases - chemically induced ; Lung Diseases - pathology ; Male ; Medical sciences ; Organic Chemicals - chemistry ; Organic Chemicals - poisoning ; Paint ; Pneumology ; Respiratory system : syndromes and miscellaneous diseases ; Solvents ; Solvents - chemistry ; Solvents - poisoning ; Toxicology</subject><ispartof>Clinical toxicology (Philadelphia, Pa.), 2007-01, Vol.45 (3), p.287-289</ispartof><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c509t-b7bed3c5e7e63f9a7c01433916dfd8fedee2101be68acfdc6a8c20eb56f2f6d03</citedby><cites>FETCH-LOGICAL-c509t-b7bed3c5e7e63f9a7c01433916dfd8fedee2101be68acfdc6a8c20eb56f2f6d03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18700754$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17453883$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ZAIDI, Shakeel A</creatorcontrib><creatorcontrib>SHAW, Asha N</creatorcontrib><creatorcontrib>PATEL, Monila N</creatorcontrib><creatorcontrib>SHAH, Vipul V</creatorcontrib><creatorcontrib>RAJENDRAN, Dipa</creatorcontrib><creatorcontrib>SHAH, Bhaumik P</creatorcontrib><creatorcontrib>SINHA, Sukesh N</creatorcontrib><creatorcontrib>GANDHI, Sumitra J</creatorcontrib><creatorcontrib>SAIYED, Habibullah N</creatorcontrib><title>Multi-organ toxicity and death following acute unintentional inhalation of paint thinner fumes</title><title>Clinical toxicology (Philadelphia, Pa.)</title><addtitle>Clin Toxicol (Phila)</addtitle><description>Paint thinners containing a mixture of volatile organic solvents have considerable potential for solvent abuse. Deaths from solvent inhalation have been reported but most of them relate to intentional solvent abuse and occur soon after exposure. Accidental death due to unintentional inhalation of solvent vapors can also occur suddenly but more often, death results from late complications secondary to multi-organ toxicity. Malfunctioning of the cardiorespiratory, renal, and central nervous systems as a result of latent-toxic effects of solvent exposure has received little attention.
An adult male unintentionally inhaled an excessive amount of paint thinner vapors and immediately developed central nervous system effects, followed by severe cardiorespiratory and renal pathologies that ultimately led to death 11 days after exposure.
Acute unintentional inhalation of paint thinner fumes resulted in serious multi-organ toxicity and death. This case strongly suggests the need to employ suitable precautionary measures while handling volatile organic solvents in a confined area.</description><subject>Adolescent</subject><subject>Air Pollutants - poisoning</subject><subject>Biological and medical sciences</subject><subject>Brain Diseases, Metabolic - chemically induced</subject><subject>Brain Diseases, Metabolic - pathology</subject><subject>Cardiovascular Diseases - chemically induced</subject><subject>Cardiovascular Diseases - pathology</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>Fatal Outcome</subject><subject>Gas Chromatography-Mass Spectrometry</subject><subject>Humans</subject><subject>Inhalation Exposure - adverse effects</subject><subject>Kidney Diseases - chemically induced</subject><subject>Kidney Diseases - pathology</subject><subject>Lung Diseases - chemically induced</subject><subject>Lung Diseases - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Organic Chemicals - chemistry</subject><subject>Organic Chemicals - poisoning</subject><subject>Paint</subject><subject>Pneumology</subject><subject>Respiratory system : syndromes and miscellaneous diseases</subject><subject>Solvents</subject><subject>Solvents - chemistry</subject><subject>Solvents - poisoning</subject><subject>Toxicology</subject><issn>1556-3650</issn><issn>1556-9519</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNqFkDtvFTEQhS0EIg_4AWmQG-g2jNfrVxlFIYkURAMtK689znXka1_WXkH-PfcqK6VIkWpmznznFIeQMwbnDDR8ZUJILgVIYMCZMuwNOT5onRHMvF33A3BETmp9AOB6MOw9OWJqEFxrfkx-f19Si12Z722mrfyLLrZHarOnHm3b0FBSKn9jvqfWLQ3pkmNumFss2SYa88YmezhoCXRn9z_aNjFnnGlYtlg_kHfBpoof13lKfn27-nl50939uL69vLjrnADTuklN6LkTqFDyYKxywAbODZM-eB3QI_YM2IRSWxe8k1a7HnASMvRBeuCn5MtT7m4ufxasbdzG6jAlm7EsdexBDb025lWQGcmVUmIPsifQzaXWGcO4m-PWzo8jg_HQ_vii_b3n0xq-TFv0z4617j3weQVsdTaF2WYX6zOnFYASA_8P2B6Opw</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>ZAIDI, Shakeel A</creator><creator>SHAW, Asha N</creator><creator>PATEL, Monila N</creator><creator>SHAH, Vipul V</creator><creator>RAJENDRAN, Dipa</creator><creator>SHAH, Bhaumik P</creator><creator>SINHA, Sukesh N</creator><creator>GANDHI, Sumitra J</creator><creator>SAIYED, Habibullah N</creator><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope><scope>7ST</scope><scope>SOI</scope></search><sort><creationdate>20070101</creationdate><title>Multi-organ toxicity and death following acute unintentional inhalation of paint thinner fumes</title><author>ZAIDI, Shakeel A ; SHAW, Asha N ; PATEL, Monila N ; SHAH, Vipul V ; RAJENDRAN, Dipa ; SHAH, Bhaumik P ; SINHA, Sukesh N ; GANDHI, Sumitra J ; SAIYED, Habibullah N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c509t-b7bed3c5e7e63f9a7c01433916dfd8fedee2101be68acfdc6a8c20eb56f2f6d03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Air Pollutants - poisoning</topic><topic>Biological and medical sciences</topic><topic>Brain Diseases, Metabolic - chemically induced</topic><topic>Brain Diseases, Metabolic - pathology</topic><topic>Cardiovascular Diseases - chemically induced</topic><topic>Cardiovascular Diseases - pathology</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>Fatal Outcome</topic><topic>Gas Chromatography-Mass Spectrometry</topic><topic>Humans</topic><topic>Inhalation Exposure - adverse effects</topic><topic>Kidney Diseases - chemically induced</topic><topic>Kidney Diseases - pathology</topic><topic>Lung Diseases - chemically induced</topic><topic>Lung Diseases - pathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Organic Chemicals - chemistry</topic><topic>Organic Chemicals - poisoning</topic><topic>Paint</topic><topic>Pneumology</topic><topic>Respiratory system : syndromes and miscellaneous diseases</topic><topic>Solvents</topic><topic>Solvents - chemistry</topic><topic>Solvents - poisoning</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ZAIDI, Shakeel A</creatorcontrib><creatorcontrib>SHAW, Asha N</creatorcontrib><creatorcontrib>PATEL, Monila N</creatorcontrib><creatorcontrib>SHAH, Vipul V</creatorcontrib><creatorcontrib>RAJENDRAN, Dipa</creatorcontrib><creatorcontrib>SHAH, Bhaumik P</creatorcontrib><creatorcontrib>SINHA, Sukesh N</creatorcontrib><creatorcontrib>GANDHI, Sumitra J</creatorcontrib><creatorcontrib>SAIYED, Habibullah N</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Environment Abstracts</collection><jtitle>Clinical toxicology (Philadelphia, Pa.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ZAIDI, Shakeel A</au><au>SHAW, Asha N</au><au>PATEL, Monila N</au><au>SHAH, Vipul V</au><au>RAJENDRAN, Dipa</au><au>SHAH, Bhaumik P</au><au>SINHA, Sukesh N</au><au>GANDHI, Sumitra J</au><au>SAIYED, Habibullah N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multi-organ toxicity and death following acute unintentional inhalation of paint thinner fumes</atitle><jtitle>Clinical toxicology (Philadelphia, Pa.)</jtitle><addtitle>Clin Toxicol (Phila)</addtitle><date>2007-01-01</date><risdate>2007</risdate><volume>45</volume><issue>3</issue><spage>287</spage><epage>289</epage><pages>287-289</pages><issn>1556-3650</issn><eissn>1556-9519</eissn><abstract>Paint thinners containing a mixture of volatile organic solvents have considerable potential for solvent abuse. Deaths from solvent inhalation have been reported but most of them relate to intentional solvent abuse and occur soon after exposure. Accidental death due to unintentional inhalation of solvent vapors can also occur suddenly but more often, death results from late complications secondary to multi-organ toxicity. Malfunctioning of the cardiorespiratory, renal, and central nervous systems as a result of latent-toxic effects of solvent exposure has received little attention.
An adult male unintentionally inhaled an excessive amount of paint thinner vapors and immediately developed central nervous system effects, followed by severe cardiorespiratory and renal pathologies that ultimately led to death 11 days after exposure.
Acute unintentional inhalation of paint thinner fumes resulted in serious multi-organ toxicity and death. This case strongly suggests the need to employ suitable precautionary measures while handling volatile organic solvents in a confined area.</abstract><cop>Philadelphia, PA</cop><pub>Taylor & Francis</pub><pmid>17453883</pmid><doi>10.1080/15563650601031791</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1556-3650 |
| ispartof | Clinical toxicology (Philadelphia, Pa.), 2007-01, Vol.45 (3), p.287-289 |
| issn | 1556-3650 1556-9519 |
| language | eng |
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| source | Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list) |
| subjects | Adolescent Air Pollutants - poisoning Biological and medical sciences Brain Diseases, Metabolic - chemically induced Brain Diseases, Metabolic - pathology Cardiovascular Diseases - chemically induced Cardiovascular Diseases - pathology Chemical and industrial products toxicology. Toxic occupational diseases Fatal Outcome Gas Chromatography-Mass Spectrometry Humans Inhalation Exposure - adverse effects Kidney Diseases - chemically induced Kidney Diseases - pathology Lung Diseases - chemically induced Lung Diseases - pathology Male Medical sciences Organic Chemicals - chemistry Organic Chemicals - poisoning Paint Pneumology Respiratory system : syndromes and miscellaneous diseases Solvents Solvents - chemistry Solvents - poisoning Toxicology |
| title | Multi-organ toxicity and death following acute unintentional inhalation of paint thinner fumes |
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