Stable Colloidal Dispersions of C sub(60) Fullerenes in Water: Evidence for Genotoxicity

Stable colloidal dispersions of C sub(60) fullerenes in water were examined. The extended mixing method resulted in the formation of larger and less negatively charged nC sub(60) colloids than nC sub(60) prepared by ethanol to water solvent exchange. Genotoxicity of these suspensions was evaluated w...

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Bibliographic Details
Published in:Environmental science & technology 2006-12, Vol.40 (23), p.7394-7394
Main Authors: Dhawan, Alok, Taurozzi, Julian S, Pandey, Alok K, Shan, Wenqian, Miller, Sarah M, Hashsham, Syed A, Tarabara, Volodymyr V
Format: Article
Language:English
Subjects:
Olea
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Summary:Stable colloidal dispersions of C sub(60) fullerenes in water were examined. The extended mixing method resulted in the formation of larger and less negatively charged nC sub(60) colloids than nC sub(60) prepared by ethanol to water solvent exchange. Genotoxicity of these suspensions was evaluated with respect to human lymphocytes using single-cell gel electrophoresis assay. The assay demonstrated genotoxicity for both types of suspensions with a strong correlation between the genotoxic response and nC sub(60) concentration, and with genotoxicity observed at concentrations as low as 2.2 mu g/L for aqu/nC sub(60) and 4.2 mu g/L for EtOH/nC sub(60). The results represented the first genotoxicity data for colloidal fullerenes produced by simple mixing in water.
ISSN:0013-936X
1520-5851
DOI:10.1021/es0609708