DNA Sensing by Field-Effect Transistors Based on Networks of Carbon Nanotubes

We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evid...

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Bibliographic Details
Published in:Journal of the American Chemical Society 2007-01, Vol.129 (46), p.14427-14432
Main Authors: Gui, Ee Ling, Li, Lain-Jong, Zhang, Keke, Xu, Yangping, Dong, Xiaochen, Ho, Xinning, Lee, Pooi See, Kasim, Johnson, Shen, Z X, Rogers, JohnA, Mhaisalkar, S G
Format: Article
Language:English
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Summary:We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.
ISSN:1272-7863
1520-5126
DOI:10.1021/ja075176gPII:S0002-7863(07)05176-1