Occupational Exposure to Dibutyl Phthalate Among Manicurists

Objective: To measure manicurists' exposure to dibutyl phthalate (DBP) at work and to determine whether workplace characteristics influence this exposure. DBP is a reproductive and developmental toxicant in rats and is used in nail polish to hold color and prevent chipping. Methods: Pre- and po...

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Bibliographic Details
Published in:Journal of occupational and environmental medicine 2008-06, Vol.50 (6), p.705-711
Main Authors: Kwapniewski, Rachel, Kozaczka, Sarah, Hauser, Russ, Silva, Manori J., Calafat, Antonia M., Duty, Susan M.
Format: Article
Language:English
Subjects:
Adult
Air Pollutants, Occupational - analysis
Beauty Culture
Beauty salons
Biological and medical sciences
Chemical and industrial products toxicology. Toxic occupational diseases
Dibutyl Phthalate - analysis
Dibutyl Phthalate - urine
Environmental Monitoring - statistics & numerical data
Gloves, Protective - utilization
Human exposure
Humans
Medical sciences
Occupational Exposure - analysis
Occupational hazards
Occupational health
ORIGINAL ARTICLES
Plasticizers - analysis
Protective Clothing
Toxicology
Various organic compounds
Ventilation
Work environment
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Summary:Objective: To measure manicurists' exposure to dibutyl phthalate (DBP) at work and to determine whether workplace characteristics influence this exposure. DBP is a reproductive and developmental toxicant in rats and is used in nail polish to hold color and prevent chipping. Methods: Pre- and postshift spot urine samples were collected from 40 manicurists. Linear regression compared the relationship between the log of the cross-shift differences in urinary phthalate monoester metabolite concentrations and use of workplace exposure control methods. Results: There was a statistically significant cross-shift increase of 17.4 ng/mL in the urinary concentration of mono-n-butyl phthalate, the major metabolite of DBP. Use of gloves reduced mono-n-butyl phthalate concentrations by 15.1 ng/mL below the preshift concentration compared with a 20.5 ng/mL increase if gloves were not worn. Conclusions: Manicurists are occupationally exposed to DBP and glove use may minimize this exposure.
ISSN:1076-2752
1536-5948
DOI:10.1097/JOM.0b013e3181651571