Loading…
Taste Loss and Recovery Following Radiation Therapy
Previous investigators have reported deficits in taste acuity in patients following radiation therapy for oropharyngeal cancer. In the present longitudinal study, 13 patients (mean age = 51.6 yrs) received conventional or hyperfractionated radiotherapy (63–76.8 Gy) for primary tumors of the orophary...
Saved in:
| Published in: | Journal of dental research 2006-07, Vol.85 (7), p.608-611 |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c494t-1d719c129ad71254030404740d0b557abc27a1859a077100a46cc3b26a4162673 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c494t-1d719c129ad71254030404740d0b557abc27a1859a077100a46cc3b26a4162673 |
| container_end_page | 611 |
| container_issue | 7 |
| container_start_page | 608 |
| container_title | Journal of dental research |
| container_volume | 85 |
| creator | Sandow, P.L. Hejrat-Yazdi, M. Heft, M.W. |
| description | Previous investigators have reported deficits in taste acuity in patients following radiation therapy for oropharyngeal cancer. In the present longitudinal study, 13 patients (mean age = 51.6 yrs) received conventional or hyperfractionated radiotherapy (63–76.8 Gy) for primary tumors of the oropharynx. One or both parotid glands and at least two-thirds of the tongue were included in the radiation field. Smell recognition and taste detection thresholds were determined at baseline, 1 month, 6 months, and 1 year post-radiation. Differences for smell recognition and the 4 taste qualities were assessed (independently) at the 4 time intervals, with a one-way ANOVA. Smell recognition was unaffected by radiation. There were significant elevations in thresholds for sweet (p < 0.005), salty (p < 0.005), bitter (p < 0.005), and sour (p< 0.001) during radiation therapy that were restored to baseline levels at 6 months and 1 year after radiation. This study demonstrated that radiation-induced taste deficits can be recovered by 6 months. |
| doi_str_mv | 10.1177/154405910608500705 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_20833740</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_154405910608500705</sage_id><sourcerecordid>20833740</sourcerecordid><originalsourceid>FETCH-LOGICAL-c494t-1d719c129ad71254030404740d0b557abc27a1859a077100a46cc3b26a4162673</originalsourceid><addsrcrecordid>eNp9kE9Lw0AQxRdRbK1-AQ8SPHiLnf2XzR5FrAoFodRzmGy2NSXN1t1E6bd3SwsFBU8zDL958-YRck3hnlKlxlQKAVJTyCCXAArkCRnuhuluekqGAIylwIUckIsQVgBUs5yfkwHNlM5zqYeEzzF0Npm6EBJsq2RmjfuyfptMXNO477pdJjOsauxq1ybzD-txs70kZwtsgr061BF5nzzNH1_S6dvz6-PDNDVCiy6llaLaUKYxNkwK4CBAKAEVlFIqLA1TSKMLBKUoAIrMGF6yDAXNWKb4iNztdTfeffY2dMW6DsY2DbbW9aFgkHMe9SJ4-wtcud630VtktJA8lyJCbA8ZH5_1dlFsfL1Gvy0oFLs8i795xqWbg3Jfrm11XDkEGIHxHgi4tMez_0j-AA3ZeYo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>209453854</pqid></control><display><type>article</type><title>Taste Loss and Recovery Following Radiation Therapy</title><source>SAGE:Jisc Collections:SAGE Journals Read and Publish 2023-2024: Reading List</source><creator>Sandow, P.L. ; Hejrat-Yazdi, M. ; Heft, M.W.</creator><creatorcontrib>Sandow, P.L. ; Hejrat-Yazdi, M. ; Heft, M.W.</creatorcontrib><description>Previous investigators have reported deficits in taste acuity in patients following radiation therapy for oropharyngeal cancer. In the present longitudinal study, 13 patients (mean age = 51.6 yrs) received conventional or hyperfractionated radiotherapy (63–76.8 Gy) for primary tumors of the oropharynx. One or both parotid glands and at least two-thirds of the tongue were included in the radiation field. Smell recognition and taste detection thresholds were determined at baseline, 1 month, 6 months, and 1 year post-radiation. Differences for smell recognition and the 4 taste qualities were assessed (independently) at the 4 time intervals, with a one-way ANOVA. Smell recognition was unaffected by radiation. There were significant elevations in thresholds for sweet (p < 0.005), salty (p < 0.005), bitter (p < 0.005), and sour (p< 0.001) during radiation therapy that were restored to baseline levels at 6 months and 1 year after radiation. This study demonstrated that radiation-induced taste deficits can be recovered by 6 months.</description><identifier>ISSN: 0022-0345</identifier><identifier>EISSN: 1544-0591</identifier><identifier>DOI: 10.1177/154405910608500705</identifier><identifier>PMID: 16798859</identifier><identifier>CODEN: JDREAF</identifier><language>eng</language><publisher>United States: SAGE Publications</publisher><subject>Adult ; Aged ; Ageusia - etiology ; Analysis of Variance ; Cranial Irradiation - adverse effects ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Oropharyngeal Neoplasms - radiotherapy ; Recovery of Function ; Taste Buds - radiation effects</subject><ispartof>Journal of dental research, 2006-07, Vol.85 (7), p.608-611</ispartof><rights>International and American Associations for Dental Research</rights><rights>Copyright American Association for Dental Research/American Academy of Implant Dentistry Jul 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-1d719c129ad71254030404740d0b557abc27a1859a077100a46cc3b26a4162673</citedby><cites>FETCH-LOGICAL-c494t-1d719c129ad71254030404740d0b557abc27a1859a077100a46cc3b26a4162673</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925,79364</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16798859$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sandow, P.L.</creatorcontrib><creatorcontrib>Hejrat-Yazdi, M.</creatorcontrib><creatorcontrib>Heft, M.W.</creatorcontrib><title>Taste Loss and Recovery Following Radiation Therapy</title><title>Journal of dental research</title><addtitle>J Dent Res</addtitle><description>Previous investigators have reported deficits in taste acuity in patients following radiation therapy for oropharyngeal cancer. In the present longitudinal study, 13 patients (mean age = 51.6 yrs) received conventional or hyperfractionated radiotherapy (63–76.8 Gy) for primary tumors of the oropharynx. One or both parotid glands and at least two-thirds of the tongue were included in the radiation field. Smell recognition and taste detection thresholds were determined at baseline, 1 month, 6 months, and 1 year post-radiation. Differences for smell recognition and the 4 taste qualities were assessed (independently) at the 4 time intervals, with a one-way ANOVA. Smell recognition was unaffected by radiation. There were significant elevations in thresholds for sweet (p < 0.005), salty (p < 0.005), bitter (p < 0.005), and sour (p< 0.001) during radiation therapy that were restored to baseline levels at 6 months and 1 year after radiation. This study demonstrated that radiation-induced taste deficits can be recovered by 6 months.</description><subject>Adult</subject><subject>Aged</subject><subject>Ageusia - etiology</subject><subject>Analysis of Variance</subject><subject>Cranial Irradiation - adverse effects</subject><subject>Female</subject><subject>Humans</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Oropharyngeal Neoplasms - radiotherapy</subject><subject>Recovery of Function</subject><subject>Taste Buds - radiation effects</subject><issn>0022-0345</issn><issn>1544-0591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNp9kE9Lw0AQxRdRbK1-AQ8SPHiLnf2XzR5FrAoFodRzmGy2NSXN1t1E6bd3SwsFBU8zDL958-YRck3hnlKlxlQKAVJTyCCXAArkCRnuhuluekqGAIylwIUckIsQVgBUs5yfkwHNlM5zqYeEzzF0Npm6EBJsq2RmjfuyfptMXNO477pdJjOsauxq1ybzD-txs70kZwtsgr061BF5nzzNH1_S6dvz6-PDNDVCiy6llaLaUKYxNkwK4CBAKAEVlFIqLA1TSKMLBKUoAIrMGF6yDAXNWKb4iNztdTfeffY2dMW6DsY2DbbW9aFgkHMe9SJ4-wtcud630VtktJA8lyJCbA8ZH5_1dlFsfL1Gvy0oFLs8i795xqWbg3Jfrm11XDkEGIHxHgi4tMez_0j-AA3ZeYo</recordid><startdate>20060701</startdate><enddate>20060701</enddate><creator>Sandow, P.L.</creator><creator>Hejrat-Yazdi, M.</creator><creator>Heft, M.W.</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RQ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>U9A</scope><scope>7QR</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20060701</creationdate><title>Taste Loss and Recovery Following Radiation Therapy</title><author>Sandow, P.L. ; Hejrat-Yazdi, M. ; Heft, M.W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c494t-1d719c129ad71254030404740d0b557abc27a1859a077100a46cc3b26a4162673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Ageusia - etiology</topic><topic>Analysis of Variance</topic><topic>Cranial Irradiation - adverse effects</topic><topic>Female</topic><topic>Humans</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Oropharyngeal Neoplasms - radiotherapy</topic><topic>Recovery of Function</topic><topic>Taste Buds - radiation effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sandow, P.L.</creatorcontrib><creatorcontrib>Hejrat-Yazdi, M.</creatorcontrib><creatorcontrib>Heft, M.W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Career & Technical Education Database</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>Chemoreception Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of dental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sandow, P.L.</au><au>Hejrat-Yazdi, M.</au><au>Heft, M.W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Taste Loss and Recovery Following Radiation Therapy</atitle><jtitle>Journal of dental research</jtitle><addtitle>J Dent Res</addtitle><date>2006-07-01</date><risdate>2006</risdate><volume>85</volume><issue>7</issue><spage>608</spage><epage>611</epage><pages>608-611</pages><issn>0022-0345</issn><eissn>1544-0591</eissn><coden>JDREAF</coden><abstract>Previous investigators have reported deficits in taste acuity in patients following radiation therapy for oropharyngeal cancer. In the present longitudinal study, 13 patients (mean age = 51.6 yrs) received conventional or hyperfractionated radiotherapy (63–76.8 Gy) for primary tumors of the oropharynx. One or both parotid glands and at least two-thirds of the tongue were included in the radiation field. Smell recognition and taste detection thresholds were determined at baseline, 1 month, 6 months, and 1 year post-radiation. Differences for smell recognition and the 4 taste qualities were assessed (independently) at the 4 time intervals, with a one-way ANOVA. Smell recognition was unaffected by radiation. There were significant elevations in thresholds for sweet (p < 0.005), salty (p < 0.005), bitter (p < 0.005), and sour (p< 0.001) during radiation therapy that were restored to baseline levels at 6 months and 1 year after radiation. This study demonstrated that radiation-induced taste deficits can be recovered by 6 months.</abstract><cop>United States</cop><pub>SAGE Publications</pub><pmid>16798859</pmid><doi>10.1177/154405910608500705</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-0345 |
| ispartof | Journal of dental research, 2006-07, Vol.85 (7), p.608-611 |
| issn | 0022-0345 1544-0591 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_20833740 |
| source | SAGE:Jisc Collections:SAGE Journals Read and Publish 2023-2024: Reading List |
| subjects | Adult Aged Ageusia - etiology Analysis of Variance Cranial Irradiation - adverse effects Female Humans Longitudinal Studies Male Middle Aged Oropharyngeal Neoplasms - radiotherapy Recovery of Function Taste Buds - radiation effects |
| title | Taste Loss and Recovery Following Radiation Therapy |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T15%3A16%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Taste%20Loss%20and%20Recovery%20Following%20Radiation%20Therapy&rft.jtitle=Journal%20of%20dental%20research&rft.au=Sandow,%20P.L.&rft.date=2006-07-01&rft.volume=85&rft.issue=7&rft.spage=608&rft.epage=611&rft.pages=608-611&rft.issn=0022-0345&rft.eissn=1544-0591&rft.coden=JDREAF&rft_id=info:doi/10.1177/154405910608500705&rft_dat=%3Cproquest_cross%3E20833740%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c494t-1d719c129ad71254030404740d0b557abc27a1859a077100a46cc3b26a4162673%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=209453854&rft_id=info:pmid/16798859&rft_sage_id=10.1177_154405910608500705&rfr_iscdi=true |