Prediction of stillbirth in Holstein‐Friesian dairy cattle by measuring metabolic and endocrine parameters during the peripartal period

• Published in: Reproduction in domestic animals 2018-12, Vol.53 (6), p.1434-1441
• Main Authors: Szenci, Otto, Abdelmegeid, Mohamed K., Solymosi, Norbert, Brydl, Endre, Bajcsy, Csaba Á., Biksi, Imre, Kulcsár, Margit
• Format: Article
• Language: English
• Subjects: Animals; Aspartate aminotransferase; Body Weight; Bovidae; Calcium; Calcium phosphates; Calves; Cattle; Cattle - blood; Cattle - metabolism; Cattle - physiology; Cortisol; Dairy cattle; Dystocia - veterinary; Esterification; Farms; Fatty acids; Female; Growth factors; Hungary; Hydrocortisone - blood; Insulin; Insulin - blood; Labor Presentation; Magnesium; Male; Metabolism; Parameters; Parity; Parturition - metabolism; Parturition - physiology; Predictions; Pregnancy - metabolism; Pregnancy - physiology; Prevalence; Proteins; Somatomedins - analysis; Stillbirth; Stillbirth - epidemiology; Stillbirth - veterinary; Thyroid hormones; Thyroxine; Thyroxine - blood; Triiodothyronine; Triiodothyronine - blood; Urea
• ISSN: 0936-6768; 1439-0531
• DOI: 10.1111/rda.13276

Contents The aim of this study was to determine whether measurements of certain metabolic (non‐esterified fatty acid, β‐hydroxybutyrate, glucose, total protein, albumin, urea‐nitrogen, aspartate aminotransferase, total calcium, inorganic phosphate and magnesium) and endocrine (cortisol, thyroxine, triiodothyronine, insulin and insulin‐like growth factor) parameters in the peripartal period (2 months and 3 weeks before expected calving and within 1 hr after calving) were related to the prevalence of stillbirth in a Holstein‐Friesian farm in Hungary. All together 155 dairy cattle (n = 22 primiparous, n = 133 multiparous cows) were monitored in two separate years selected randomly on the same farm. Overall, the prevalence of stillbirth was 11% (n = 17). Significantly higher stillbirth rate was detected in case of heifer calvings (OR = 8.5), and when ≥3 assistants (severe dystocia; OR = 8.9) were needed to assist at calving while the body condition score of the dams, the bodyweight and gender of the newborn calves, the percentage of posterior presentations had no significant effect on stillbirth rate. There were no significant differences between cows without and with stillbirth in case of any measured metabolic and endocrine parameters during the examined time periods. At the same time, some of the metabolic parameters (TP, AST and inorg.P) showed some significant differences among the stillbirth groups, but stillbirth could not be predicted by the measured parameters and therefore the role of metabolic and/or endocrine changes on the prevalence of stillbirth needs further elucidation.