In vitro trypanocidal effect of methanolic extract of some Nigerian savannah plants

Methanol extracts from twenty three plants harvested from the Savannah vegetation belt of Nigeria were analyzed in vitro for trypanocidal activity against Trypanosoma brucei brucei and Trypanosoma congolense at concentrations of 4 mg/ml, 0.4 mg/ml and 0.04 mg/ml. Extracts of Khaya senegalensis, Pili...

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Bibliographic Details
Published in:African journal of biotechnology 2003-09, Vol.2 (9), p.317-321
Main Authors: Atawodi, SE, Bulus, T, Ibrahim, S, Ameh, DA, Nok, A J, Mamman, M, Galadima, M
Format: Article
Language:English
Subjects:
Adansonia digitata
Cassytha
Khaya senegalensis
Parkia
Prosopis africana
Securidaca
Striga
Trypanosoma brucei brucei
Trypanosoma congolense
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Summary:Methanol extracts from twenty three plants harvested from the Savannah vegetation belt of Nigeria were analyzed in vitro for trypanocidal activity against Trypanosoma brucei brucei and Trypanosoma congolense at concentrations of 4 mg/ml, 0.4 mg/ml and 0.04 mg/ml. Extracts of Khaya senegalensis, Piliostigma reticulatum, Securidaca longepedunculata and Terminalia avicennoides were strongly trypanocidal to both organisms while extracts of Anchomanes difformis, Cassytha spp, Lannea kerstingii, Parkia clappertioniana, Striga spp, Adansonia digitata and Prosopis africana were trypanocidal to either T. brucei brucei or T. congolense. These findings provide evidence of the effects of some plants in the traditional management of trypanosomiasis.
ISSN:1684-5315
1684-5315
DOI:10.5897/AJB2003.000-1065