Pediatric extracorporeal cardiopulmonary resuscitation settled in an emergency department for a propafenone intentional intoxication

The use of drugs in suicide attempts is becoming more and more frequent among adolescents. Intentional intoxication with propafenone is very rare and mainly reported in adults associated with other drugs. The therapeutic approach is symptomatic, since there is no specific antidote for propafenone. W...

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Bibliographic Details
Published in:The American journal of emergency medicine 2018-11, Vol.36 (11), p.2132.e1-2132.e3
Main Authors: Marano, Marco, Goffredo, Bianca M., Pisani, Mara, Filippelli, Sergio, Cecchetti, Corrado, Drago, Fabrizio, Barbieri, Maria A., Nunziata, Joseph, Genuini, Leonardo, Di Nardo, Matteo
Format: Article
Language:English
Subjects:
Adolescents
Blood pressure
Cardiac arrhythmia
Cardiopulmonary resuscitation
CPR
Drug dosages
Electrocardiography
Emergency medical care
Emergency medical services
Extracorporeal cardiopulmonary resuscitation
Ingestion
Intoxication
Laboratories
Patients
Pediatrics
Plasma
Poisoning
Suicide
Suicides & suicide attempts
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Summary:The use of drugs in suicide attempts is becoming more and more frequent among adolescents. Intentional intoxication with propafenone is very rare and mainly reported in adults associated with other drugs. The therapeutic approach is symptomatic, since there is no specific antidote for propafenone. We present a pediatric case of intentional ingestion of 1.8 g of propafenone that caused refractory cardiogenic shock. The patient was successfully rescued with extracorporeal cardiopulmonary resuscitation in the emergency department of a secondary level peripheral hospital.
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2018.08.001