Impact of concomitant tricuspid regurgitation on long-term outcomes in severe aortic stenosis

• Published in: European heart journal cardiovascular imaging 2019-03, Vol.20 (3), p.353-360
• Main Authors: Amano, Masashi, Izumi, Chisato, Taniguchi, Tomohiko, Morimoto, Takeshi, Miyake, Makoto, Nishimura, Shunsuke, Kitai, Takeshi, Kato, Takao, Kadota, Kazushige, Ando, Kenji, Furukawa, Yutaka, Inada, Tsukasa, Inoko, Moriaki, Ishii, Katsuhisa, Sakaguchi, Genichi, Yamazaki, Fumio, Koyama, Tadaaki, Komiya, Tatsuhiko, Yamanaka, Kazuo, Nishiwaki, Noboru, Kanemitsu, Naoki, Saga, Toshihiko, Ogawa, Tatsuya, Nakayama, Shogo, Tsuneyoshi, Hiroshi, Iwakura, Atsushi, Shiraga, Kotaro, Hanyu, Michiya, Ohno, Nobuhisa, Fukumoto, Atsushi, Yamada, Tomoyuki, Nishizawa, Junichiro, Esaki, Jiro, Minatoya, Kenji, Nakagawa, Yoshihisa, Kimura, Takeshi
• Format: Article
• Language: English
• ISSN: 2047-2404; 2047-2412
• DOI: 10.1093/ehjci/jey105

Abstract Aims Tricuspid regurgitation (TR) has been reported to be associated with worse survival in various heart diseases, but there are few data in aortic stenosis (AS). Methods and results In the Contemporary Outcomes after Surgery and Medical Treatment in Patients with Severe Aortic Stenosis (CURRENT AS) Registry enrolling 3815 consecutive patients with severe AS, there were 628 patients with moderate or severe TR (TR group) and 3187 patients with no or mild TR (no TR group). The study patients were subdivided into the initial aortic valve replacement (AVR) stratum (n = 1197) and the conservative stratum (n = 2618) according to treatment strategy. The primary outcome measure was a composite of aortic valve-related death or hospitalization due to heart failure. The 5-year freedom rate from the primary outcome measure was significantly lower in the TR group than in the no TR group (49.1% vs. 67.3%, P