Dietary acid load and cardiometabolic risk in the Polish adult population

The potential influence of disorders of acid/base homeostasis on cardiovascular risk factors has been suggested. The aim of the study was to estimate the relationship between dietary acid load and the prevalence of cardiovascular disease and the prevalence and intensity of cardiovascular risk factor...

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Published in:Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2018-10, Vol.27 (10), p.1347-1345
Main Authors: Kucharska, Alicja M, Szostak-Węgierek, Dorota E, Waśkiewicz, Anna, Piotrowski, Walerian, Stepaniak, Urszula, Pająk, Andrzej, Kozakiewicz, Krystyna, Tykarski, Andrzej, Rutkowski, Marcin, Bielecki, Wojciech J, Drygas, Wojciech
Format: Article
Language:English
Subjects:
Acid-Base Imbalance - epidemiology
Acids - metabolism
Adult
Aged
Aged, 80 and over
Biomarkers - blood
Biomarkers - metabolism
Cardiovascular Diseases - epidemiology
Cross-Sectional Studies
Diabetes Mellitus, Type 2 - epidemiology
Diet
Diet Surveys
Female
Humans
Hypertension - epidemiology
Hypertension - metabolism
Kidney - metabolism
Male
Metabolic Syndrome - epidemiology
Middle Aged
Nutrition Assessment
Poland - epidemiology
Risk Factors
Surveys and Questionnaires
Young Adult
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Summary:The potential influence of disorders of acid/base homeostasis on cardiovascular risk factors has been suggested. The aim of the study was to estimate the relationship between dietary acid load and the prevalence of cardiovascular disease and the prevalence and intensity of cardiovascular risk factors (i.e., hypertension, diabetes, overweight and obesity, dyslipidemia) in the Polish adult population. Data was derived from a cross-sectional survey of a random sample of 6,170 Polish residents aged 20+ (Multi-Center National Population Health Examination Survey, WOBASZ II study), including anthropometric and laboratory measurements, and estimates of nutrient intakes by 24-h recall. Dietary acid/ base load was assessed as potential renal acid load (PRAL) and net endogenous acid production (NEAP). The median PRAL and NEAP values for the whole study population were: PRAL -3.85 mEq/day and NEAP 39.79 mEq/day. The prevalence of overweight and obesity, both in males and females, tended to decrease across tertiles of PRAL and to increase across tertiles of NEAP. In females, the values of several metabolic characteristics differed across tertiles of NEAP. After adjustment for age and waist circumference, these relationships did not persist, but the prevalence of diabetes was found to increase across tertiles of PRAL (p for trend
ISSN:1899-5276
DOI:10.17219/acem/69733