Nephropathia epidemica with a 6-week incubation period after occupational exposure to Puumala hantavirus

Abstract Serological and molecular evidence showed that a German female student became infected by Puumala hantavirus during mice trapping efforts in Finland. The incubation period before exhibiting clinical signs of nephropathia epidemica was as long as 6 weeks. Phylogenetic analysis of PUUV nuclei...

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Bibliographic Details
Published in:Journal of clinical virology 2009-01, Vol.44 (1), p.99-101
Main Authors: Kramski, Marit, Achazi, Katharina, Klempa, Boris, Krüger, Detlev H
Format: Article
Language:English
Subjects:
Adult
Allergy and Immunology
Animals
Female
Finland
Hantavirus
Hemorrhagic fever with renal syndrome
Hemorrhagic Fever with Renal Syndrome - physiopathology
Hemorrhagic Fever with Renal Syndrome - virology
Humans
Incubation period
Infectious Disease
Infectious Disease Incubation Period
Mice
Molecular Sequence Data
Occupational Exposure
Phylogeny
Puumala virus - classification
Puumala virus - genetics
Puumala virus - isolation & purification
RNA, Viral - genetics
Sequence Analysis, DNA
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Summary:Abstract Serological and molecular evidence showed that a German female student became infected by Puumala hantavirus during mice trapping efforts in Finland. The incubation period before exhibiting clinical signs of nephropathia epidemica was as long as 6 weeks. Phylogenetic analysis of PUUV nucleic acid sequences amplified from the patient demonstrate that she was infected by the PUUV strain circulating at the place of her occupational exposure in Finland.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2008.10.005