The epidemiological impact and significance of carbapenem resistance in Pseudomonas aeruginosa bloodstream infections: a matched case-case-control analysis

A case-case-control investigation (N = 255 patients) explored the epidemiology of carbapenem-resistant Pseudomonas aeruginosa (CRPA). Recent exposure to carbapenems and a rapidly fatal condition should prompt practitioners to shorten delays in initiating appropriate therapy, which can adversely impa...

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Bibliographic Details
Published in:Infection control and hospital epidemiology 2018-10, Vol.39 (10), p.1262-1265
Main Authors: Aviv, Tzach, Lazarovitch, Tsillia, Katz, David, Zaidenstein, Ronit, Dadon, Mor, Daniel, Chen, Tal-Jasper, Ruthy, Kaye, Keith S, Marchaim, Dror
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Anti-Bacterial Agents - pharmacology
Antibiotics
Bacteremia - epidemiology
Bacteremia - mortality
beta-Lactam Resistance
Blood pressure
Carbapenems - pharmacology
Cardiovascular disease
Case-Control Studies
Clinical outcomes
Disease prevention
Epidemiology
Female
Heart
Hospital Mortality
Humans
Infections
Israel - epidemiology
Long term health care
Male
Middle Aged
Mortality
Ostomy
Prostheses
Pseudomonas aeruginosa
Pseudomonas Infections - epidemiology
Pseudomonas Infections - mortality
Risk Factors
Survival Analysis
Tumor necrosis factor-TNF
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Summary:A case-case-control investigation (N = 255 patients) explored the epidemiology of carbapenem-resistant Pseudomonas aeruginosa (CRPA). Recent exposure to carbapenems and a rapidly fatal condition should prompt practitioners to shorten delays in initiating appropriate therapy, which can adversely impact CRPA outcomes, as opposed to the isolated impact of the carbapenem resistance determinant.
ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2018.181