Compensatory hypertrophy of the liver after external beam radiotherapy for primary liver cancer

Purpose We investigated whether external beam radiotherapy (EBRT) could induce compensatory liver hypertrophy in liver cancers and assessed related clinical factors. Methods A total of 82 consecutive patients receiving EBRT for hepatocellular carcinoma ( n  = 77) or cholangiocarcinoma ( n  = 5) from...

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Bibliographic Details
Published in:Strahlentherapie und Onkologie 2018-11, Vol.194 (11), p.1017-1029
Main Authors: Rim, Chai Hong, Park, Sangjoon, Woo, Joong Yeol, Seong, Jinsil
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Bile Duct Neoplasms - radiotherapy
Carcinoma, Hepatocellular - radiotherapy
Chemoembolization, Therapeutic
Chemotherapy
Chemotherapy, Adjuvant
Cholangiocarcinoma
Cholangiocarcinoma - radiotherapy
Combined Modality Therapy
Female
Follow-Up Studies
Humans
Infusions, Intra-Arterial
Liver
Liver - pathology
Liver - radiation effects
Liver cancer
Liver Failure - pathology
Liver Neoplasms - radiotherapy
Lobes
Male
Medicine
Medicine & Public Health
Middle Aged
Multivariate analysis
Neoplasm Staging
Oncology
Organ Size - radiation effects
Original Article
Radiation therapy
Radiotherapy
Retrospective Studies
Subgroups
Tumors
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Summary:Purpose We investigated whether external beam radiotherapy (EBRT) could induce compensatory liver hypertrophy in liver cancers and assessed related clinical factors. Methods A total of 82 consecutive patients receiving EBRT for hepatocellular carcinoma ( n  = 77) or cholangiocarcinoma ( n  = 5) from April 2012 to June 2014 were recruited and divided into two subgroups according to tumor location in the right or left lobe. The left lateral and right lobes were considered as unirradiated volumes accordingly. Total liver volume (TLV), nontumor liver volume (NLV), left and right lobe whole volume (LLWV and RLWV, respectively), volume of liver irradiated 
ISSN:0179-7158
1439-099X
DOI:10.1007/s00066-018-1342-y