REFRACTORY CERAMIC FIBER: Toxicology, Epidemiology, and Risk Analyses - A Review

Refractory ceramic fiber (RCF) is an energy-efficient, high-temperature insulation, used principally in industrial furnaces, heaters, and reactors. Prior to the 1980s, there were few publications dealing with the potential health effects of this material. However, with the advent of higher energy co...

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Bibliographic Details
Published in:Inhalation toxicology 2000, Vol.12 (5), p.359-399
Main Authors: Mast, R W, Maxim, L D, Utell, M J, Walker, A M
Format: Article
Language:English
Subjects:
Administration, Inhalation
Air Pollutants - toxicity
Air Pollutants, Occupational - toxicity
Animals
Ceramics - classification
Ceramics - toxicity
Humans
In Vitro Techniques
Inhalation Exposure
Kaolin - classification
Kaolin - toxicity
Lung - drug effects
Mineral Fibers - classification
Mineral Fibers - toxicity
Pneumoconiosis - epidemiology
Pneumoconiosis - etiology
Risk Assessment
Toxicity Tests
United States - epidemiology
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Summary:Refractory ceramic fiber (RCF) is an energy-efficient, high-temperature insulation, used principally in industrial furnaces, heaters, and reactors. Prior to the 1980s, there were few publications dealing with the potential health effects of this material. However, with the advent of higher energy costs and the need for thermally efficient high-temperature insulating materials, production of RCF grew rapidly, as did interest in its potential health effects. This article provides a comprehensive and integrated review of the toxicology (in vitro and in vivo), epidemiology, and risk analysis literature of RCF. Based on the available literature, we conclude that an occupational exposure of 0.5 fibers per cubic centimeter (cm3) [8-h time-weighted average (8-h TWA)] results in an occupational health risk no greater than 9.1 x 10-5.
ISSN:0895-8378
1091-7691
DOI:10.1080/089583700196103