Efficacy and safety of long pulse Nd:YAG laser versus fractional erbium:YAG laser in the treatment of facial skin wrinkles

• Published in: Lasers in medical science 2019-04, Vol.34 (3), p.457-464
• Main Authors: Dadkhahfar, Sahar, Fadakar, Kaveh, Robati, Reza M.
• Format: Article
• Language: English
• Subjects: Aging; Dentistry; Double-Blind Method; Erbium; Face - radiation effects; Female; Humans; Infrared lasers; Lasers; Lasers, Solid-State - adverse effects; Lasers, Solid-State - therapeutic use; Medicine; Medicine & Public Health; Middle Aged; Neodymium lasers; Optical Devices; Optics; Original Article; Patient Satisfaction; Patients; Photonics; Quantum Optics; Semiconductor lasers; Skin; Skin Aging - radiation effects; Time Factors; Treatment Outcome; YAG lasers
• ISSN: 0268-8921; 1435-604X
• DOI: 10.1007/s10103-018-2614-6

Fractional lasers such erbium:YAG (Er:YAG) are among popular options for facial rejuvenation. Lasers with infrared wavelength ranges such as long pulse Nd:YAG have been used in nonablative rejuvenation of skin with variable outcomes. In this study, we plan to compare safety and efficacy of fractional Er:YAG and long pulse Nd:YAG for facial rejuvenation applying objective and subjective measurements. Twenty-five patients with Glogau photo aging scale of II to IV were recruited in this randomized face-split double-blind controlled trial. Individuals received three monthly treatments on two sides of the face; one side was treated by fractional Er:YAG laser and the other side by long pulse Nd:YAG laser. Outcomes were evaluated by two blinded dermatologists, patient satisfaction reports and objective measurements of cutaneous resonance running time (CRRT). Both modalities significantly improved periorbital wrinkling, nasolabial folds, dyschromia and skin laxity, and sagging of jowls ( p value