Development of an optimized broth enrichment culture medium for the isolation of Clostridium difficile

Clostridium difficile is a spore forming bacterium and the leading cause of colitis and antibiotic associated diarrhoea in the developed world. Effective recovery of spores, particularly in low numbers, is imperative to obtain accurate prevalence data, due to the low number of spores found within no...

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Bibliographic Details
Published in:Anaerobe 2018-12, Vol.54, p.92-99
Main Authors: Connor, Mairéad C., McGrath, John W., McMullan, Geoff, Marks, Nikki, Fairley, Derek J.
Format: Article
Language:English
Subjects:
Bacteriological Techniques - methods
Clostridium difficile
Clostridium difficile - growth & development
Clostridium difficile - isolation & purification
Clostridium difficile - metabolism
Clostridium Infections - microbiology
Culture media
Culture Media - chemistry
Culture Media - metabolism
Growth
Humans
Moxalactam - metabolism
Norfloxacin - metabolism
Spores
Taurocholate
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Description
Summary:Clostridium difficile is a spore forming bacterium and the leading cause of colitis and antibiotic associated diarrhoea in the developed world. Effective recovery of spores, particularly in low numbers, is imperative to obtain accurate prevalence data, due to the low number of spores found within non-clinical samples (
ISSN:1075-9964
1095-8274
DOI:10.1016/j.anaerobe.2018.08.006