Dynamic Changes and Drug-Induced Selection of Resistant Clones in a Patient With EGFR-Mutated Adenocarcinoma That Acquired T790M Mutation and Transformed to Small-Cell Lung Cancer

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Bibliographic Details
Published in:Clinical lung cancer 2018-11, Vol.19 (6), p.e843-e847
Main Authors: Iijima, Yuki, Hirotsu, Yosuke, Mochizuki, Hitoshi, Amemiya, Kenji, Oyama, Toshio, Uchida, Yoshinori, Kobayashi, Yoichi, Tsutsui, Toshiharu, Kakizaki, Yumiko, Miyashita, Yoshihiro, Omata, Masao
Format: Article
Language:English
Subjects:
Adenocarcinoma - drug therapy
Adenocarcinoma - genetics
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Carboplatin - therapeutic use
Cell Transformation, Neoplastic
Clone Cells
Drug Resistance, Neoplasm - genetics
Drug Substitution
ErbB Receptors - genetics
Etoposide - therapeutic use
Ex 19 del
Female
Humans
Lung cancer
Lung Neoplasms - drug therapy
Lung Neoplasms - genetics
Middle Aged
Mutation - genetics
Neoplasm Recurrence, Local
Neoplasm Staging
Osimertinib
Remission Induction
SCLC transformation
Small Cell Lung Carcinoma - drug therapy
Small Cell Lung Carcinoma - genetics
T790M
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ISSN:1525-7304
1938-0690
DOI:10.1016/j.cllc.2018.07.002