Antibacterial activity of irradiated extracts of Anacardium occidentale L. on multiresistant strains of Staphylococcus aureus

This study evaluated the antibacterial activity of crude and fractionated leaf extracts of Anacardium occidentale, after receiving 10 kGy from 60Co, against multiresistant strains of Staphylococcus aureus in vitro. Minimum Inhibitory Concentrations-MIC and Minimum Bacteriostatic Concentrations-MBC w...

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Bibliographic Details
Published in:Applied radiation and isotopes 2018-10, Vol.140, p.327-332
Main Authors: dos Santos, Gustavo Henrique Farias, Amaral, Ademir, da Silva, Edvane Borges
Format: Article
Language:English
Subjects:
Anacardium - chemistry
Anacardium occidentale L
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - radiation effects
Antibacterial activity
Antibacterial agents
Drug Resistance, Multiple, Bacterial
Gamma irradiation
Humans
Microbial Sensitivity Tests
Phytotherapy
Plant Extracts - administration & dosage
Plant Extracts - pharmacology
Plant Extracts - radiation effects
Radiation Dosage
Staphylococcus aureus
Staphylococcus aureus - drug effects
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Summary:This study evaluated the antibacterial activity of crude and fractionated leaf extracts of Anacardium occidentale, after receiving 10 kGy from 60Co, against multiresistant strains of Staphylococcus aureus in vitro. Minimum Inhibitory Concentrations-MIC and Minimum Bacteriostatic Concentrations-MBC were respectively assessed by serial microdilution technique in multiwall plates and Petri dishes, against standard strains and clinical isolates of multiresistant S. aureus. The results pointed out a significantly increase of the antibacterial activity of the such extracts after irradiation, emphasizing the role of gamma radiation on leaf extracts of A. occidentale to improve bioactive substances, offering new raw material for antibacterial drugs. •Fractionated leaf extracts of Anacardium occidentale were irradiated with 10 kGy from 60Co.•Antimicrobial action of irradiated extracts was tested against multiresistant strains of Staphylococcus aureus, in vitro.•The process of irradiation significantly increased the antibacterial activity of the irradiated extracts of leaves.•This research opens new possibilities to provide easy-to-obtain plant raw materials that can be used as antibacterial agents.
ISSN:0969-8043
1872-9800
DOI:10.1016/j.apradiso.2018.07.035