Dual-Porosity Hollow Carbon Spheres with Tunable Through-Holes for Multi-Guest Delivery

Dual-porosity hollow carbon spheres (DPHCs) with small mesopores (2–4 nm) and large through-holes (20–30 nm) in shells were successfully synthesized using colloidal silica as the template, small silica nanoparticles as nanomasks, and nontoxic dopamine as the carbon precursor followed by post-carboni...

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Bibliographic Details
Published in:ACS applied materials & interfaces 2018-09, Vol.10 (37), p.31664-31673
Main Authors: Wu, Xi, Si, Yinsong, Zou, Yibiao, Mao, Yuting, Li, Qiuju, Zhou, Shuxue, Chen, Min, Wu, Limin
Format: Article
Language:English
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Summary:Dual-porosity hollow carbon spheres (DPHCs) with small mesopores (2–4 nm) and large through-holes (20–30 nm) in shells were successfully synthesized using colloidal silica as the template, small silica nanoparticles as nanomasks, and nontoxic dopamine as the carbon precursor followed by post-carbonization and etching. The synthesized DPHCs were further oxidized to be hydrophilic and then used to simultaneously deliver the protein bovine serum albumin (21 × 4 × 14 nm3) and the small molecule doxorubicin (
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.8b11825