Efficacy and safety of elbasvir/grazoprevir for Japanese patients with genotype 1b chronic hepatitis C complicated by chronic kidney disease, including those undergoing hemodialysis: A post hoc analysis of a multicenter study

Background and Aim This study aimed to evaluate the efficacy and safety of elbasvir/grazoprevir in genotype 1b chronic hepatitis C Japanese patients with chronic kidney disease (CKD), including those undergoing hemodialysis. Methods This post hoc analysis of a multicenter, retrospective study includ...

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Bibliographic Details
Published in:Journal of gastroenterology and hepatology 2019-02, Vol.34 (2), p.364-369
Main Authors: Atsukawa, Masanori, Tsubota, Akihito, Toyoda, Hidenori, Takaguchi, Koichi, Kondo, Chisa, Okubo, Tomomi, Hiraoka, Atsushi, Michitaka, Kojiro, Fujioka, Shinichi, Uojima, Haruki, Watanabe, Tsunamasa, Ikeda, Hiroki, Asano, Toru, Ishikawa, Toru, Matsumoto, Yoshihiro, Abe, Hiroshi, Kato, Keizo, Tsuji, Kunihiko, Ogawa, Chikara, Shimada, Noritomo, Iio, Etsuko, Mikami, Shigeru, Tanaka, Yasuhito, Kumada, Takashi, Iwakiri, Katsuhiko
Format: Article
Language:English
Subjects:
chronic hepatitis C
chronic kidney disease
elbasvir
Epidermal growth factor receptors
Genotype & phenotype
Genotypes
Glomerular filtration rate
grazoprevir
Hemodialysis
Hepatitis
Hepatitis C
Interferon
Kidney diseases
Patients
Population studies
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Summary:Background and Aim This study aimed to evaluate the efficacy and safety of elbasvir/grazoprevir in genotype 1b chronic hepatitis C Japanese patients with chronic kidney disease (CKD), including those undergoing hemodialysis. Methods This post hoc analysis of a multicenter, retrospective study included patients who had received elbasvir/grazoprevir. CKD was defined by an estimated glomerular filtration rate (eGFR)
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.14447