(P 371) The First Trial Use of Tissue-Engineering Design on Basis of Autogenous Multipotential Stromal Cells of Adipose Tissue for Sinus-Lifting and Compensate for a Deficiency Tissues Alveolar Septum

• Published in: Tissue engineering. Part A 2008-05, Vol.14 (5), p.915-915
• Main Authors: Alekseeva, I S, Volkov, A V, Arutunyan, I V, Rzhaninova, A A, Goldshtein, D V, Kulakov, AA
• Format: Article
• Language: English
• ISSN: 1937-3341; 1937-335X

The cells technology allows to receive natural equivalents of bone tissue--tissue-engineering design on basis of multipotential stro mal cells (MMSC). The marrow or adipose tissue can be used as a source of MMSC. Cell culture MMSC was received and described according with the passport of the culture of standard proceeding. Demineralized bone matrix in the form of blocks or chips was used as a scaffold. The selection of 3D structure was determined according to clinic problem. Patient 1. Transplantation construction was executed in the area of AS after ablation "BioOss". The improvement of bone tissue and increase of width AS was detected after 1 and 3 months. Patient 2. The extraction of 14,15 at the inspection perforation of the bottom maxillary of sinuse, the absence of bone wall from the vestibular surface. On the spiral computer tomography (SCT) it was revealed, that the thickness and the width of AS amount 0.61 cm. and 0.59 cm. agreeably. The sinus lift operation with transplantation construction was made in area bottom sinus as well as increase of width of the alveolar septum. After 3 months treatment it was determined by SCT that the height of the alveolar septum amount 2.4 cm. and width 1.0 cm. Patient 3. The transplantation construction in alveolar socket, extraction 18 at operation instant. The complete regeneration of the cortical plate in the area of extraction of 18 was revealed after 3 months by SCT. After histological study of tissue revealed by reclaim every patients was detected the forming new bone tissue.