(P 249) Mechanical Properties of Tissue Engineering Scaffolds

Mechanical properties are of great importance for the clinical use of scaffolds in tissue engineering. Depending on the desired application, the scaffold may have to be very elastic to adapt itself to the size of the explant or quite rigid to support tensions for example. We synthesized polymeric sc...

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Bibliographic Details
Published in:Tissue engineering. Part A 2008-05, Vol.14 (5), p.877-877
Main Authors: Lebourg, M, Mas, J, Ribelles, JLG, Anton, J S
Format: Article
Language:English
Online Access:Get full text
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Summary:Mechanical properties are of great importance for the clinical use of scaffolds in tissue engineering. Depending on the desired application, the scaffold may have to be very elastic to adapt itself to the size of the explant or quite rigid to support tensions for example. We synthesized polymeric scaffolds with varying porosity and microstructure by mixed porogen leaching/ freeze extraction processes, and drove systematic mechanical properties measurements in compression, in order to characterize the response of scaffolds, and the influence of macro and microporosity on the observed properties. In an attempt to develop a mathematical model based on the cellular solids theory by Ashby and Gibson we designed a gradual compression test to obtain further theoretical knowledge on the collapse process of porous scaffolds.
ISSN:1937-3341
1937-335X