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Amplitude-Integrated Electroencephalography for Early Recognition of Brain Injury in Neonates with Critical Congenital Heart Disease

To study perioperative amplitude-integrated electroencephalography (aEEG) as an early marker for new brain injury in neonates requiring cardiac surgery for critical congenital heart disease (CHD). This retrospective observational cohort study investigated 76 neonates with critical CHD who underwent...

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Bibliographic Details
Published in:The Journal of pediatrics 2018-11, Vol.202, p.199-205.e1
Main Authors: Claessens, Nathalie H.P., Noorlag, Lotte, Weeke, Lauren C., Toet, Mona C., Breur, Johannes M.P.J., Algra, Selma O., Schouten, Antonius N.J., Haas, Felix, Groenendaal, Floris, Benders, Manon J.N.L., Jansen, Nicolaas J.G., de Vries, Linda S.
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Language:English
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Summary:To study perioperative amplitude-integrated electroencephalography (aEEG) as an early marker for new brain injury in neonates requiring cardiac surgery for critical congenital heart disease (CHD). This retrospective observational cohort study investigated 76 neonates with critical CHD who underwent neonatal surgery. Perioperative aEEG recordings were evaluated for background pattern (BGP), sleep-wake cycling (SWC), and ictal discharges. Spontaneous activity transient (SAT) rate, inter-SAT interval (ISI), and percentage of time with an amplitude
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2018.06.048