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Differential response to lithium between melancholic and non-melancholic unipolar depression
•The response to lithium could be greater in melancholic depressions.•Due to scarce data available and other limitations the results are preliminary.•Results are consistent with those reported with antidepressants. The purpose of this report was to review the evidence regarding the differential resp...
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| Published in: | Psychiatry research 2018-11, Vol.269, p.183-184 |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c368t-d705f8ead15812dd2ed0fbed393a911857b26b9dd14d6a88fb17d7b4621ad2013 |
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| cites | cdi_FETCH-LOGICAL-c368t-d705f8ead15812dd2ed0fbed393a911857b26b9dd14d6a88fb17d7b4621ad2013 |
| container_end_page | 184 |
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| container_start_page | 183 |
| container_title | Psychiatry research |
| container_volume | 269 |
| creator | Valerio, Marina P. Martino, Diego J. |
| description | •The response to lithium could be greater in melancholic depressions.•Due to scarce data available and other limitations the results are preliminary.•Results are consistent with those reported with antidepressants.
The purpose of this report was to review the evidence regarding the differential response to lithium treatment between patients with unipolar melancholic and non-melancholic depression. Three studies suggest that the prophylactic effect of lithium in maintenance treatment may be greater in melancholic depression. Another study reported that melancholic symptoms, such as weight loss and psychomotor disturbances, predict a better response to lithium augmentation. These preliminary data suggest that the response to lithium may be greater in melancholic than in non-melancholic depression, which could be the focus of further research. |
| doi_str_mv | 10.1016/j.psychres.2018.08.077 |
| format | article |
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The purpose of this report was to review the evidence regarding the differential response to lithium treatment between patients with unipolar melancholic and non-melancholic depression. Three studies suggest that the prophylactic effect of lithium in maintenance treatment may be greater in melancholic depression. Another study reported that melancholic symptoms, such as weight loss and psychomotor disturbances, predict a better response to lithium augmentation. These preliminary data suggest that the response to lithium may be greater in melancholic than in non-melancholic depression, which could be the focus of further research.</description><identifier>ISSN: 0165-1781</identifier><identifier>EISSN: 1872-7123</identifier><identifier>DOI: 10.1016/j.psychres.2018.08.077</identifier><identifier>PMID: 30149276</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>Adult ; Depressive Disorder - diagnosis ; Depressive Disorder - drug therapy ; Depressive Disorder - psychology ; Depressive Disorder, Major - diagnosis ; Depressive Disorder, Major - drug therapy ; Depressive Disorder, Major - psychology ; Endogenous ; Female ; Humans ; Lithium - therapeutic use ; Major depressive disorder ; Male ; Middle Aged ; Treatment ; Treatment Outcome</subject><ispartof>Psychiatry research, 2018-11, Vol.269, p.183-184</ispartof><rights>2018 Elsevier B.V.</rights><rights>Copyright © 2018 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c368t-d705f8ead15812dd2ed0fbed393a911857b26b9dd14d6a88fb17d7b4621ad2013</citedby><cites>FETCH-LOGICAL-c368t-d705f8ead15812dd2ed0fbed393a911857b26b9dd14d6a88fb17d7b4621ad2013</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30149276$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Valerio, Marina P.</creatorcontrib><creatorcontrib>Martino, Diego J.</creatorcontrib><title>Differential response to lithium between melancholic and non-melancholic unipolar depression</title><title>Psychiatry research</title><addtitle>Psychiatry Res</addtitle><description>•The response to lithium could be greater in melancholic depressions.•Due to scarce data available and other limitations the results are preliminary.•Results are consistent with those reported with antidepressants.
The purpose of this report was to review the evidence regarding the differential response to lithium treatment between patients with unipolar melancholic and non-melancholic depression. Three studies suggest that the prophylactic effect of lithium in maintenance treatment may be greater in melancholic depression. Another study reported that melancholic symptoms, such as weight loss and psychomotor disturbances, predict a better response to lithium augmentation. These preliminary data suggest that the response to lithium may be greater in melancholic than in non-melancholic depression, which could be the focus of further research.</description><subject>Adult</subject><subject>Depressive Disorder - diagnosis</subject><subject>Depressive Disorder - drug therapy</subject><subject>Depressive Disorder - psychology</subject><subject>Depressive Disorder, Major - diagnosis</subject><subject>Depressive Disorder, Major - drug therapy</subject><subject>Depressive Disorder, Major - psychology</subject><subject>Endogenous</subject><subject>Female</subject><subject>Humans</subject><subject>Lithium - therapeutic use</subject><subject>Major depressive disorder</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Treatment</subject><subject>Treatment Outcome</subject><issn>0165-1781</issn><issn>1872-7123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNqFkE1LxDAQhoMoun78haVHL10z6bZJb4rfIHjRmxDSZMpmaZOatMr-e7OsijdhYGB45p15X0LmQBdAobpYL4a40auAccEoiAVNxfkemYHgLOfAin0yS2CZAxdwRI5jXFNKGdT1ITkqKCxrxqsZebuxbYsB3WhVlyW5wbuI2eizzo4rO_VZg-Mnost67JTTK99ZnSlnMudd_nc2OTv4ToXM4JB0ovXulBy0qot49t1PyOvd7cv1Q_70fP94ffWU66ISY244LVuBykApgBnD0NC2QVPUhaoBRMkbVjW1MbA0lRKibYAb3iwrBsok98UJOd_pDsG_TxhH2duosUvPoZ-iZLQuS8YYFQmtdqgOPsaArRyC7VXYSKBym6xcy59k5TZZSVNxnhbn3zempkfzu_YTZQIudwAmpx8Wg4zaotNobEA9SuPtfze-ALXfkAw</recordid><startdate>201811</startdate><enddate>201811</enddate><creator>Valerio, Marina P.</creator><creator>Martino, Diego J.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201811</creationdate><title>Differential response to lithium between melancholic and non-melancholic unipolar depression</title><author>Valerio, Marina P. ; Martino, Diego J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c368t-d705f8ead15812dd2ed0fbed393a911857b26b9dd14d6a88fb17d7b4621ad2013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Depressive Disorder - diagnosis</topic><topic>Depressive Disorder - drug therapy</topic><topic>Depressive Disorder - psychology</topic><topic>Depressive Disorder, Major - diagnosis</topic><topic>Depressive Disorder, Major - drug therapy</topic><topic>Depressive Disorder, Major - psychology</topic><topic>Endogenous</topic><topic>Female</topic><topic>Humans</topic><topic>Lithium - therapeutic use</topic><topic>Major depressive disorder</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Treatment</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Valerio, Marina P.</creatorcontrib><creatorcontrib>Martino, Diego J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatry research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Valerio, Marina P.</au><au>Martino, Diego J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Differential response to lithium between melancholic and non-melancholic unipolar depression</atitle><jtitle>Psychiatry research</jtitle><addtitle>Psychiatry Res</addtitle><date>2018-11</date><risdate>2018</risdate><volume>269</volume><spage>183</spage><epage>184</epage><pages>183-184</pages><issn>0165-1781</issn><eissn>1872-7123</eissn><abstract>•The response to lithium could be greater in melancholic depressions.•Due to scarce data available and other limitations the results are preliminary.•Results are consistent with those reported with antidepressants.
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| ispartof | Psychiatry research, 2018-11, Vol.269, p.183-184 |
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| language | eng |
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| source | ScienceDirect Freedom Collection |
| subjects | Adult Depressive Disorder - diagnosis Depressive Disorder - drug therapy Depressive Disorder - psychology Depressive Disorder, Major - diagnosis Depressive Disorder, Major - drug therapy Depressive Disorder, Major - psychology Endogenous Female Humans Lithium - therapeutic use Major depressive disorder Male Middle Aged Treatment Treatment Outcome |
| title | Differential response to lithium between melancholic and non-melancholic unipolar depression |
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