Obstructive Sleep Apnea in Children with Down Syndrome: Demographic, Clinical, and Polysomnographic Features

Objectives To evaluate demographic, clinical, and polysomnographic features of children with Down syndrome suspected of having obstructive sleep apnea. To identify factors that predict severe obstructive sleep apnea among children with Down syndrome. Study Design Case series with chart review. Setti...

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Bibliographic Details
Published in:Otolaryngology-head and neck surgery 2019-01, Vol.160 (1), p.150-157
Main Authors: Chamseddin, Bahir H., Johnson, Romaine F., Mitchell, Ron B.
Format: Article
Language:English
Subjects:
Down syndrome
obesity
obstructive sleep apnea
pediatrics
polysomnography
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Summary:Objectives To evaluate demographic, clinical, and polysomnographic features of children with Down syndrome suspected of having obstructive sleep apnea. To identify factors that predict severe obstructive sleep apnea among children with Down syndrome. Study Design Case series with chart review. Setting Children’s Medical Center Dallas / University of Texas Southwestern Medical Center. Subject and Methods Demographic, clinical, and polysomnographic data were collected for children with Down syndrome aged 2 to 18 years. Simple and multivariable regression models were used to study predictors of severe obstructive sleep apnea (apnea-hypopnea index ≥10). P≤ .05 was considered significant. Results A total of 106 children with Down syndrome were included, with 89 (84%)
ISSN:0194-5998
1097-6817
DOI:10.1177/0194599818797308