Optical Coherence Tomography Predictors for Recurrent Restenosis After Paclitaxel-Coated Balloon Angioplasty for Drug-Eluting Stent Restenosis

Background: Little is known of the relationship between optical coherence tomography (OCT) findings and recurrent restenosis after paclitaxel-coated balloon (PCB) angioplasty for drug-eluting stent in-stent restenosis (DES-ISR). To identify the predictors of recurrent restenosis after PCB angioplast...

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Bibliographic Details
Published in:Circulation Journal 2018/10/25, Vol.82(11), pp.2820-2828
Main Authors: Miura, Katsuya, Tada, Takeshi, Habara, Seiji, Kuwayama, Akimune, Shimada, Takenobu, Ohya, Masanobu, Murai, Ryosuke, Amano, Hidewo, Kubo, Shunsuke, Otsuru, Suguru, Tanaka, Hiroyuki, Fuku, Yasushi, Goto, Tsuyoshi, Kadota, Kazushige
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Angioplasty, Balloon, Coronary
Coronary Angiography
Coronary Restenosis - diagnostic imaging
Drug-Eluting Stents
Female
Follow-Up Studies
Graft Occlusion, Vascular - diagnostic imaging
Graft Occlusion, Vascular - etiology
Humans
In-stent restenosis
Male
Middle Aged
Optical coherence tomography
Paclitaxel - administration & dosage
Paclitaxel-coated balloon
Tomography, Optical Coherence
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Summary:Background: Little is known of the relationship between optical coherence tomography (OCT) findings and recurrent restenosis after paclitaxel-coated balloon (PCB) angioplasty for drug-eluting stent in-stent restenosis (DES-ISR). To identify the predictors of recurrent restenosis after PCB angioplasty, we investigated quantitative and qualitative OCT findings during PCB angioplasty for DES-ISR. Methods and Results: In all, 222 DES-ISR lesions treated by PCB angioplasty with OCT assessment and followed-up angiographically at 6 months were divided into restenotic and non-restenotic lesions on the basis of the presence or absence of restenosis at follow-up. There was a significantly higher proportion of the heterogeneous tissue pattern in restenotic than non-restenotic lesions (26.5% vs. 11.0%, respectively; P=0.02). The OCT-derived post-procedural minimal lumen and stent areas were significantly smaller in restenotic lesions, but the intima area was similar in both groups. Post-procedural stent underexpansion, defined as a stent diameter : size of the previous stent ratio
ISSN:1346-9843
1347-4820
1347-4820
DOI:10.1253/circj.CJ-18-0464