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Paraneoplastic stiff person syndrome with small cell carcinoma of the bladder and anti-Ri antibodies
•The stiff person syndrome (SPS) is difficult to diagnose and to treat.•Paraneoplastic SPS with anti-Ri antibodies is less known.•Early antitumoral therapy should be the first step in these cases.•SPS has not been described in bladder cancer to date.•This case report expands the spectrum of paraneop...
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| Published in: | Clinical neurology and neurosurgery 2018-10, Vol.173, p.194-195 |
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| Main Authors: | , , , , |
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| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c396t-68cb0e43e2294137f29101c0fcdb039e963218cb3425341cb284ecfe4044ae233 |
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| cites | cdi_FETCH-LOGICAL-c396t-68cb0e43e2294137f29101c0fcdb039e963218cb3425341cb284ecfe4044ae233 |
| container_end_page | 195 |
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| container_start_page | 194 |
| container_title | Clinical neurology and neurosurgery |
| container_volume | 173 |
| creator | de Albóniga-Chindurza, Asier Riva, Elena Jiménez-Huete, Adolfo Graus, Francesc Franch, Oriol |
| description | •The stiff person syndrome (SPS) is difficult to diagnose and to treat.•Paraneoplastic SPS with anti-Ri antibodies is less known.•Early antitumoral therapy should be the first step in these cases.•SPS has not been described in bladder cancer to date.•This case report expands the spectrum of paraneoplastic SPS.
The stiff person syndrome is a rare neurological disorder, difficult to diagnose and to treat. Paraneoplastic patients usually present amphiphysin antibodies but the association with anti-Ri antibodies is less known. We present a case report of paraneoplastic SPS, small cell carcinoma of the bladder and anti-Ri antibodies. |
| doi_str_mv | 10.1016/j.clineuro.2018.08.020 |
| format | article |
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The stiff person syndrome is a rare neurological disorder, difficult to diagnose and to treat. Paraneoplastic patients usually present amphiphysin antibodies but the association with anti-Ri antibodies is less known. We present a case report of paraneoplastic SPS, small cell carcinoma of the bladder and anti-Ri antibodies.</description><identifier>ISSN: 0303-8467</identifier><identifier>EISSN: 1872-6968</identifier><identifier>DOI: 10.1016/j.clineuro.2018.08.020</identifier><identifier>PMID: 30165320</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Antibodies ; Antigens ; Autoantibodies - immunology ; Bladder cancer ; Cancer therapies ; Carcinoma, Small Cell - complications ; Chemotherapy ; Electromyography ; Glutamate Decarboxylase - immunology ; Humans ; Immunoglobulins ; Lymphatic system ; Male ; Middle Aged ; Nervous System Diseases - complications ; Nervous System Diseases - immunology ; Neuroimmunology ; Neurology ; Paraneoplastic ; Stiff person ; Stiff-Person Syndrome - complications ; Urinary Bladder - immunology ; Urinary Bladder Neoplasms - complications ; Urinary Bladder Neoplasms - immunology</subject><ispartof>Clinical neurology and neurosurgery, 2018-10, Vol.173, p.194-195</ispartof><rights>2018 Elsevier B.V.</rights><rights>Copyright © 2018 Elsevier B.V. All rights reserved.</rights><rights>Copyright Elsevier Limited Oct 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-68cb0e43e2294137f29101c0fcdb039e963218cb3425341cb284ecfe4044ae233</citedby><cites>FETCH-LOGICAL-c396t-68cb0e43e2294137f29101c0fcdb039e963218cb3425341cb284ecfe4044ae233</cites><orcidid>0000-0002-3770-8534</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30165320$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Albóniga-Chindurza, Asier</creatorcontrib><creatorcontrib>Riva, Elena</creatorcontrib><creatorcontrib>Jiménez-Huete, Adolfo</creatorcontrib><creatorcontrib>Graus, Francesc</creatorcontrib><creatorcontrib>Franch, Oriol</creatorcontrib><title>Paraneoplastic stiff person syndrome with small cell carcinoma of the bladder and anti-Ri antibodies</title><title>Clinical neurology and neurosurgery</title><addtitle>Clin Neurol Neurosurg</addtitle><description>•The stiff person syndrome (SPS) is difficult to diagnose and to treat.•Paraneoplastic SPS with anti-Ri antibodies is less known.•Early antitumoral therapy should be the first step in these cases.•SPS has not been described in bladder cancer to date.•This case report expands the spectrum of paraneoplastic SPS.
The stiff person syndrome is a rare neurological disorder, difficult to diagnose and to treat. Paraneoplastic patients usually present amphiphysin antibodies but the association with anti-Ri antibodies is less known. 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The stiff person syndrome is a rare neurological disorder, difficult to diagnose and to treat. Paraneoplastic patients usually present amphiphysin antibodies but the association with anti-Ri antibodies is less known. We present a case report of paraneoplastic SPS, small cell carcinoma of the bladder and anti-Ri antibodies.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>30165320</pmid><doi>10.1016/j.clineuro.2018.08.020</doi><tpages>2</tpages><orcidid>https://orcid.org/0000-0002-3770-8534</orcidid></addata></record> |
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| ispartof | Clinical neurology and neurosurgery, 2018-10, Vol.173, p.194-195 |
| issn | 0303-8467 1872-6968 |
| language | eng |
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| source | ScienceDirect Journals |
| subjects | Antibodies Antigens Autoantibodies - immunology Bladder cancer Cancer therapies Carcinoma, Small Cell - complications Chemotherapy Electromyography Glutamate Decarboxylase - immunology Humans Immunoglobulins Lymphatic system Male Middle Aged Nervous System Diseases - complications Nervous System Diseases - immunology Neuroimmunology Neurology Paraneoplastic Stiff person Stiff-Person Syndrome - complications Urinary Bladder - immunology Urinary Bladder Neoplasms - complications Urinary Bladder Neoplasms - immunology |
| title | Paraneoplastic stiff person syndrome with small cell carcinoma of the bladder and anti-Ri antibodies |
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